4-Chlorobenzene-1,2-diol

CAS NO.：2138-22-9
Empirical Formula: C6H5ClO2
Molecular Weight: 144.56
MDL number: MFCD00059614
EINECS: 218-381-9
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:36

What is 4-Chlorobenzene-1,2-diol?

The Uses of 4-Chlorobenzene-1,2-diol

4-chlorocatechol was a major degradation product of 4-chloro-2-aminophenol (4C2AP)1. The degradation of 4-chlorocatechol was catalyzed by cphA-I enzyme2.

What are the applications of Application

4-Chlorocatechol is a chloro-substituted catechol compound

Definition

ChEBI: A chlorocatechol that is catechol substituted by a chloro group at position 4.

Synthesis Reference(s)

Tetrahedron Letters, 33, p. 865, 1992 DOI: 10.1016/S0040-4039(00)91561-2

General Description

4-chlorocatechol was a major degradation product of 4-chloro-2-aminophenol (4C2AP). The degradation of 4-chlorocatechol was catalyzed by cphA-I enzyme.

Properties of 4-Chlorobenzene-1,2-diol

Melting point:	90-94 °C (lit.)
Boiling point:	140°C 10,5mm
Density	1.2558 (rough estimate)
refractive index	1.4620 (estimate)
storage temp.	Inert atmosphere,Room Temperature
solubility	Chloroform (Slightly), Methanol (Slightly)
pka	8.84±0.10(Predicted)
form	powder to crystal
color	White to Light yellow to Light orange
CAS DataBase Reference	2138-22-9(CAS DataBase Reference)

Safety information for 4-Chlorobenzene-1,2-diol

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.