4-Chloro-3-nitrobenzenesulfonyl chloride

CAS NO.：97-08-5
Empirical Formula: C6H3Cl2NO4S
Molecular Weight: 256.06
MDL number: MFCD00007440
EINECS: 202-558-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-15 19:00:21

What is 4-Chloro-3-nitrobenzenesulfonyl chloride?

Chemical properties

LIGHT BROWN CRYSTALLINE POWDER

The Uses of 4-Chloro-3-nitrobenzenesulfonyl chloride

4-Chloro-3-nitrobenzenesulfonyl Chloride is used in the synthesis of novel sulfonamide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones which increases melanin synthesis in murine B16 cells.

The Uses of 4-Chloro-3-nitrobenzenesulfonyl chloride

4-Chloro-3-nitrobenzenesulfonyl chloride can be used:

In the preparation of functionalized 1H-indenes via copper-catalyzed arylative cyclization.
As a precursor in the synthesis of N-arylsulfonyl-3-acylindole arylcarbonyl hydrazone derivatives that show potential nematicidal activity.
As a key starting material in the synthesis of sulfonamide analogs of ferrostatin-1 (fer-1), which possess good ferroptosis inhibition property.
In the synthesis of 4-chloro-3-nitrobenzene thiol.

Properties of 4-Chloro-3-nitrobenzenesulfonyl chloride

Melting point:	59-60 °C (lit.)
Boiling point:	356°C (rough estimate)
Density	1.696 (estimate)
refractive index	1.6000 (estimate)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble in Toluene
form	Crystalline Powder
color	Light brown
Sensitive	Moisture Sensitive
BRN	1978600
CAS DataBase Reference	97-08-5(CAS DataBase Reference)
NIST Chemistry Reference	Benzenesulfonyl chloride, 4-chloro-3-nitro-(97-08-5)
EPA Substance Registry System	Benzenesulfonyl chloride, 4-chloro-3-nitro- (97-08-5)

Safety information for 4-Chloro-3-nitrobenzenesulfonyl chloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H290:Corrosive to Metals H314:Skin corrosion/irritation H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P234:Keep only in original container. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P310:Immediately call a POISON CENTER or doctor/physician. P390:Absorb spillage to prevent material damage. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. P406:Store in corrosive resistant/… container with a resistant inner liner. P501:Dispose of contents/container to..…