4-Bromophenylboronic acid

Synonym(s):(p-Bromophenyl)boronic acid;p-Bromobenzeneboronic acid;p-Bromophenylboric acid;4-Bromobenzeneboronic acid;4-Bromophenylboric acid

CAS NO.：5467-74-3
Empirical Formula: C6H6BBrO2
Molecular Weight: 200.83
MDL number: MFCD00002104
EINECS: 226-779-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 4-Bromophenylboronic acid?

Chemical properties

white to light yellow crystal powde

The Uses of 4-Bromophenylboronic acid

Labelled 4-Bromophenylboronic Acid (B686545). 4-Bromophenylboric acid is used in the preparation of arylboronates as inhibitors of fatty acid amide hydrolase.

The Uses of 4-Bromophenylboronic acid

suzuki reaction

The Uses of 4-Bromophenylboronic acid

4-Bromobenzeneboronic acid is a reagent used for Palladium catalyzed Suzuki-Miyaura cross-couplings, Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence. It is also used in the preparation of Protein modulators and enzymatic and kinase inhibitors, Gallate-based obovatol analogs with potential anti-tumor activity. It is used as a reagent for Copper-mediated ligandless aerobic fluoroalkylation of arylboronic acids with fluoroalkyl iodides, Pd-catalyzed arylative cyclization of alkyne-tethered enals or enones via carbopalladation of alkynes, Copper-catalyzed cross-couplings.

Properties of 4-Bromophenylboronic acid

Melting point:	284-288 °C (lit.)
Boiling point:	315.0±44.0 °C(Predicted)
Density	1.67±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
form	Crystalline Powder
pka	8.32±0.10(Predicted)
color	Off-white to light beige
Water Solubility	Soluble in methanol. Insoluble in water.
BRN	2936347
CAS DataBase Reference	5467-74-3(CAS DataBase Reference)

Safety information for 4-Bromophenylboronic acid

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.