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HomeProduct name list4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN Structural

What is 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN?

Chemical properties

Light Greenish-Yellow Powder

The Uses of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

4-Bromomethyl-6,7-dimethoxycoumarin was used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It was also used as derivatization reagent:

  • for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography
  • in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
  • for determination of carboxylic acids in chromatographic detection

The Uses of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

A fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids

The Uses of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

4-Bromomethyl-6,7-dimethoxycoumarin is used as fluorescent labeling reagent for the reversed-phase HPLC separation and detection of carboxylic acids. It is also used as derivatization reagent: for quantitation of clofibric, bezafibric and fenofibric acids in liver by liquid chromatography, in determination of the concentration of tripeptide glutathione by matrix-assisted laser desorption ionization time-of-flight mass spectrometry and for determination of carboxylic acids in chromatographic detection.

What are the applications of Application

4-(Bromomethyl)-6,7-dimethoxycoumarin is an HPLC fluorescent labeling reagent

Properties of 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

Melting point: 212-216 °C(lit.)
Density  1.6176 (rough estimate)
refractive index  1.4490 (estimate)
storage temp.  Inert atmosphere,2-8°C
solubility  Soluble in acetonitrile, dichloromethane, N,N-dimethylformamide, methanol
form  Powder
color  Yellow crystals or powder
Water Solubility  Insoluble in water.
λmax 348 nm (MeOH)
BRN  4750487
Major Application Electrostatic imaging process; resists; printed circuit boards; semiconductor devices
Biological Applications Analyzing bile acid; anticancer agents; identifying bacteria; identifying/measuring lauric acid metabolites; measuring cyclosporine; studying/monitoring early stages of protein folding;treating gastrointestinal diseases; derivatization reagent for carboxylic acids; as a substrate for measuring lauric acid hydroxylase activity
CAS DataBase Reference 88404-25-5(CAS DataBase Reference)

Safety information for 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 4-BROMOMETHYL-6,7-DIMETHOXYCOUMARIN

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