4-METHYLESCULETIN

CAS NO.：529-84-0
Empirical Formula: C10H8O4
Molecular Weight: 192.17
MDL number: MFCD00006859
EINECS: 208-470-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-31 13:32:20

What is 4-METHYLESCULETIN?

Chemical properties

GREY POWDER

The Uses of 4-METHYLESCULETIN

6,7-Dihydroxy-4-methylcoumarin is suitable as a pH-indicator.

What are the applications of Application

6,7-Dihydroxy-4-methylcoumarin is a product suitable as a pH-indicator

Definition

ChEBI: 6,7-dihydroxy-4-methylcoumarin is a hydroxycoumarin that is 4-methylcuomarin which is substituted by hydroxy groups at positions 3 and 4. A hyaluronan synthesis inhibitor. It has also been used as a fluorescent sensor to monitor the consumption of a boronic acid in Suzuki coupling reactions; fluorescence is readily detectable by the naked eye using a standard 365 nm UV lamp. It has a role as a hyaluronan synthesis inhibitor, an antioxidant and an anti-inflammatory agent.

Properties of 4-METHYLESCULETIN

Melting point:	274-276 °C(lit.)
Boiling point:	248.14°C (rough estimate)
Density	1.0825 (rough estimate)
refractive index	1.4440 (estimate)
storage temp.	Sealed in dry,2-8°C
solubility	DMF: soluble
form	powder
pka	8.72(at 25℃)
color	Light brown
PH Range	Colorless (4.0) to blue 1 uorescent (6.2)
λmax	348nm, 292nm
BRN	162550
Major Application	Electroluminescent device, photoresists, photography, analytical reagent, cosmetics, hair dye, shampoo, antioxidant, hypotensive agent, antiimfiammatroy agent, antiviral agent, multidrug resistance (MDR) modulator, inhibitory effect onmelanin biosynthesis, protective agent against DNA damage, antimutagenic agent, detection of tumor cell-specific cytotoxicity, antiproliferative againt against cancer cells, analysis of human pancreatice cancer cell activity, chondroprotective agent
CAS DataBase Reference	529-84-0(CAS DataBase Reference)
EPA Substance Registry System	4-Methylesculetin (529-84-0)

Safety information for 4-METHYLESCULETIN

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H303:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.