4-Bromobutyric acid

CAS NO.：2623-87-2
Empirical Formula: C4H7BrO2
Molecular Weight: 167
MDL number: MFCD00002817
EINECS: 220-083-9
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-21 22:41:43

What is 4-Bromobutyric acid?

Chemical properties

light brown low melting crystals

The Uses of 4-Bromobutyric acid

4-Bromobutyric acid is used as a bifunctional cross-linker and as a pharmaceutical intermediate. It is also used to synthesize 4-Bromobutyryl chloride.

What are the applications of Application

4-Bromobutyric acid is a bifunctional cross-linker

Synthesis

4-Bromobutyric acid may be produced by a reaction of Y-butyrolactone with hydrogen bromide. The hydrogen bromide to be used may be gas or an aqueous Solution thereof. The reaction temperature is usually about 10 to 100°C., and the amount of hydrogen bromide to be used is usually about 1 to 10 moles per mole of Y-butyrolactone.

Properties of 4-Bromobutyric acid

Melting point:	30-31 °C (lit.)
Boiling point:	128-131 °C/11 mmHg (lit.)
Density	1.4397 (rough estimate)
refractive index	1.4730 (estimate)
Flash point:	115 °C
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Chloroform (Sparingly), DMSO, Methanol (Slightly), Water (Slightly)
pka	4.51±0.10(Predicted)
form	Low Melting Crystals
color	Light brown
Water Solubility	Soluble in water and dilute alkali.
Sensitive	Light Sensitive
BRN	1743056
CAS DataBase Reference	2623-87-2(CAS DataBase Reference)
NIST Chemistry Reference	4-Bromobutyric acid(2623-87-2)
EPA Substance Registry System	4-Bromobutyric acid (2623-87-2)

Safety information for 4-Bromobutyric acid

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.