4-Bromo-2-methoxypyridine
- CAS NO.：100367-39-3
- Empirical Formula: C6H6BrNO
- Molecular Weight: 188.02
- MDL number: MFCD08277268
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 4-Bromo-2-methoxypyridine?
The Uses of 4-Bromo-2-methoxypyridine
4-Bromo-2-methoxypyridine used in the synhesis of Imidazo [1, 2-a] pyrimidines. Suzuki coupling between 4-methoxyphenylboronic acid and 4-bromo-2-methoxypyridine affords 1, 5-disubstituted pyridones. Starting material used in a synthesis of crown-ester-bipyridines and viologens via sodium or nickel reductive coupling, side chain oxidation and esterification.
Properties of 4-Bromo-2-methoxypyridine
| Melting point: | 25-26℃ |
| Boiling point: | 87℃/15mm |
| Density | 1.530±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 3.76±0.10(Predicted) |
| form | Low Melting Solid |
| color | Off-white to pale yellow |
| Water Solubility | Slightly soluble in water. |
Safety information for 4-Bromo-2-methoxypyridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 4-Bromo-2-methoxypyridine
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