4-Amino-2-(trifluoromethyl)benzonitrile

Synonym(s):4-Cyano-3-trifluoromethylaniline

CAS NO.：654-70-6
Empirical Formula: C8H5F3N2
Molecular Weight: 186.13
MDL number: MFCD00042155
EINECS: 000-000-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-08-24 19:19:26

4-Amino-2-(trifluoromethyl)benzonitrile Structural

What is 4-Amino-2-(trifluoromethyl)benzonitrile?

Chemical properties

Off-White Solid

The Uses of 4-Amino-2-(trifluoromethyl)benzonitrile

4-Amino-2-(trifluoromethyl)benzonitrile is used for the preparation of benzene derivatives as non-steroidal androgen receptor modulators.

The Uses of 4-Amino-2-(trifluoromethyl)benzonitrile

4-Amino-2-(trifluoromethyl)benzonitrile can serve as starting material in the synthesis of benzimidazoles, which can act as potential candidates in the treatment of breast cancer due to their ability to inhibit the growth of endothelial cells.

Properties of 4-Amino-2-(trifluoromethyl)benzonitrile

Melting point:	141-145 °C(lit.)
Boiling point:	294.5±40.0 °C(Predicted)
Density	1.37±0.1 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Sparingly), Methanol (Slightly)
form	Powder
pka	0.50±0.10(Predicted)
color	White to off-white
BRN	3278074
InChI	InChI=1S/C8H5F3N2/c9-8(10,11)7-3-6(13)2-1-5(7)4-12/h1-3H,13H2
CAS DataBase Reference	654-70-6(CAS DataBase Reference)
NIST Chemistry Reference	5-Amino-2-cyanobenzotrifluoride(654-70-6)

Safety information for 4-Amino-2-(trifluoromethyl)benzonitrile

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H317:Sensitisation, Skin
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.