N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide
- CAS NO.:90357-51-0
- Empirical Formula: C12H9F3N2O2
- Molecular Weight: 270.21
- MDL number: MFCD08460201
- EINECS: 618-536-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide?
The Uses of N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyl-2-oxiranecarboxamide, is an intermediate in synthesis of more complex pharmaceutical compounds. It is used in the synthesis of potential impurities of Bicalutamide (B382000), which is an oral nonsteroidal, anti-androgen drug used for prostate cancer.
Properties of N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide
Melting point: | 151-152 °C |
Boiling point: | 436.4±45.0 °C(Predicted) |
Density | 1.42±0.1 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 12.08±0.70(Predicted) |
color | White to Off-White |
CAS DataBase Reference | 90357-51-0(CAS DataBase Reference) |
Safety information for N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide
N-[4-Cyano-3-(trifluoromethyl)phenyl]methacrylamide epoxide manufacturer
Vanquest Pharma Pvt Ltd
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ALS INDIA LIFE SCIENCES
1Y
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product: 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropionanilide 98%
Kekule Pharma Limited
1Y
Phone:+919849798889
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product: 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropionanilide 90357-51-0 98%
Raising Sun Pharma
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product: 90357-51-0 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropionanilide 98%
ASM Organics
Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: 4'-Cyano-3'-trifluoromethyl-2,3-epoxy-2-methylpropionanilide
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
Bicalutamide
Desfluoro Bicalutamide
Bicalutamide EP Impurity K
BICALUTAMIDE-D4
N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methacrylamide
Deshydroxy Bicalutamide
Bicalutamide Impurity 2
3-(4-Fluobenzenesulfhydry)-2-hydroxyl-2-methylpropionic acid
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