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HomeProduct name listBICALUTAMIDE-D4

BICALUTAMIDE-D4

What is BICALUTAMIDE-D4?

Description

Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones. Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.

Chemical properties

BICALUTAMIDE-D4 is White Solid

The Uses of BICALUTAMIDE-D4

BICALUTAMIDE-D4 is used as an antiandrogen, antineoplastic (hormonal). (94%d4; 5.7%d3, 0.1%d1, no d0

What are the applications of Application

Bicalutamide-d4 is an androgen antagonist and antineoplastic

Properties of BICALUTAMIDE-D4

Melting point: 192-1940C
storage temp.  -20°C Freezer
solubility  Chloroform (Slightly, Heated), Methanol (Slightly, Sonicated)
form  Solid
color  White to Off-White

Safety information for BICALUTAMIDE-D4

Computed Descriptors for BICALUTAMIDE-D4

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