4-Acetoxyacetanilide
Synonym(s):p-Acetoxyacetanilide;4′-Acetoxyacetanilide;4-(Acetylamino)phenyl acetate
- CAS NO.：2623-33-8
- Empirical Formula: C10H11NO3
- Molecular Weight: 193.2
- MDL number: MFCD00059205
- EINECS: 220-077-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 4-Acetoxyacetanilide?
Chemical properties
White Solid
The Uses of 4-Acetoxyacetanilide
A synthetic impurity of Acetaminophen
The Uses of 4-Acetoxyacetanilide
analgesic, antiinflammatory
What are the applications of Application
Acetaminophen Acetate (Acetaminophen Impurity) is an acetaminophen synthetic impurity
What are the applications of Application
4′-Acetoxyacetanilide may be used as a reference standard for the determination of 4′-acetoxyacetanilide in pharmaceutical formulations by high performance liquid chromatography (HPLC) technique.
General Description
4′-Acetoxyacetanilide is an impurity of Acetaminophen, or Paracetamol as known internationally. This certified solution standard can be used for multiple HPLC applications including pharmaceutical testing, research, and Monograph testing methods. Acetaminophen belongs to a class of drugs called analgesics (pain relievers) and antipyretics (fever reducers).
Properties of 4-Acetoxyacetanilide
| Melting point: | 155°C |
| Boiling point: | 329.41°C (rough estimate) |
| Density | 1.2307 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | neat |
| pka | 14.41±0.70(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 0.32g/L(25 ºC) |
| CAS DataBase Reference | 2623-33-8(CAS DataBase Reference) |
| EPA Substance Registry System | 4-Acetoxyacetanilide (2623-33-8) |
Safety information for 4-Acetoxyacetanilide
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Acetoxyacetanilide
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