4'-CHLOROACETANILIDE
Synonym(s):4-Chloroacetanilide;Acetic acid 4-chloroanilide;N-(4-chlorophenyl)-acetamide;N-(4-Chlorophenyl)acetamide;4′-Chloroacetanilide
- CAS NO.:539-03-7
- Empirical Formula: C8H8ClNO
- Molecular Weight: 169.61
- MDL number: MFCD00000612
- EINECS: 208-707-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-25 16:21:11
What is 4'-CHLOROACETANILIDE?
Chemical properties
white or greyish-beige crystalline powder
The Uses of 4'-CHLOROACETANILIDE
4'-Chloroacetanilide is used in pharmaceutical preparations, using PGC column. And also used in the synthesis of alprazolam.
Definition
ChEBI: Acetamide substituted on nitrogen by a para-chlorophenyl group.
Synthesis Reference(s)
Tetrahedron, 52, p. 8863, 1996 DOI: 10.1016/0040-4020(96)00433-4
General Description
4′-Chloroacetanilide is the main impurity present in acetaminophen and has been quantitated by new high-performance liquid chromatography method using a mixed-mode reversed-phase/cation exchange stationary phase.
Purification Methods
Crystallise the anilide from EtOH or aqueous EtOH. [Beilstein 12 IV 1178.]
Properties of 4'-CHLOROACETANILIDE
Melting point: | 176-178 °C(lit.) |
Boiling point: | 333 °C |
Density | 1,385 g/cm3 |
refractive index | 1.5670 (estimate) |
Flash point: | 333°C |
storage temp. | 2-8°C |
solubility | dioxane: 50 mg/mL hot, clear |
form | Crystalline Powder |
pka | 14.25±0.70(Predicted) |
color | White or grayish-beige |
Water Solubility | Insoluble in water. |
Merck | 14,2111 |
BRN | 509638 |
CAS DataBase Reference | 539-03-7(CAS DataBase Reference) |
EPA Substance Registry System | 4-Chloroacetanilide (539-03-7) |
Safety information for 4'-CHLOROACETANILIDE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4'-CHLOROACETANILIDE
Abamectin manufacturer
KARPSCHEM LABORATORIES PVT. LTD.
1Y
Phone:+917249203006
Whatsapp: +91 7249203006
product: 539-03-7 Paracetamol EP Impurity J
N-(4-chlorophenyl)acetamide 96%
JSK Chemicals
1Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: 4'-Chloroacetanilide, 95% 539-03-7 99%
Molsyns Research
1Y
Phone:+91-9586858886
Whatsapp: +91- 9586858886
product: Acetaminophene Related Compound J 539-03-7 98%
Orgamine Chemicals(I) Pvt Ltd
1Y
Phone:+919820080281
Whatsapp: +91-9820080281
product: N-(4-chlorophenyl)-acetamide 539-03-7 98%
Clickchem Research LLP
1Y
Phone:+91-8140031133
Whatsapp: +91- 8140031133
product: PARACETAMOL RC J 90 % Above
Anand Agencies
Maharashtra
Phone:91-9075014125
Whatsapp: 91-9075014125
product: N-(4-chlorophenyl)-acetamide
Suvchem
Maharashtra
Phone:91-9821198699
Whatsapp: 91-9821198699
product: N-(4-chlorophenyl)-acetamide
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
4,4'-Iminodiphenol hydrochloride
4-[1-(hydroxyamino)ethylidene]cyclohexa-2,5-dien-1-one
2-Acetamidophenol
4'-Hydroxyacetophenone
3-CHLORO-4-HYDROXYACETANILIDE
2'-Hydroxyacetophenone
4-Acetoxyacetanilide
N,N'-(OXYDI-4,1-PHENYLENE)BISACETAMIDE
You may like
-
4-ChloroacetaNAide, 97% 98%View Details
539-03-7 -
539-03-7 98%View Details
539-03-7 -
p-Chloroacetanilide extrapure AR CAS 539-03-7View Details
539-03-7 -
p-Chloroacetanilide, GR 99%+ CAS 539-03-7View Details
539-03-7 -
p-Chloroacetanilide CAS 539-03-7View Details
539-03-7 -
4'-Chloroacetanilide CAS 539-03-7View Details
539-03-7 -
4-CHLOROACETANILIDE CAS 539-03-7View Details
539-03-7 -
p-Chloroacetanilide AR CAS 539-03-7View Details
539-03-7
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.