4-(2-Chloroethyl)morpholine hydrochloride

Synonym(s):2-Morpholinoethyl chloride hydrochloride;N-(2-Chloroethyl)-morpholinium chloride

CAS NO.：3647-69-6
Empirical Formula: C6H13Cl2NO
Molecular Weight: 186.08
MDL number: MFCD00012797
EINECS: 222-881-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-15 17:50:29

4-(2-Chloroethyl)morpholine hydrochloride Structural

What is 4-(2-Chloroethyl)morpholine hydrochloride?

Chemical properties

White to beige crystalline powder

The Uses of 4-(2-Chloroethyl)morpholine hydrochloride

4-(2-Chloroethyl)morpholine hydrochloride (MOC) is used as intermediate for the synthesis of pharmaceuticals (e.g. floredil, morinamide, nimorazole and pholcodine). Product Data Sheet

The Uses of 4-(2-Chloroethyl)morpholine hydrochloride

4-(2-Chloroethyl)morpholine is used in the preparation of potential DNA cross-linking antitumor agents as well as synthetic opiate analogues. 4-(2-Chloroethyl)morpholine may possess sickle-cell hemogl obin aggregation inhibiting-activity.

The Uses of 4-(2-Chloroethyl)morpholine hydrochloride

4-(2-Chloroethyl)morpholine hydrochloride (MOC) is used as intermediate for the synthesis of pharmaceuticals (e.g. floredil, morinamide, nimorazole and pholcodine). It is also used as Agrochemical Intermediates, dyestuff Intermediates.

Safety Profile

Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of Cland NOx.

Properties of 4-(2-Chloroethyl)morpholine hydrochloride

Melting point:	180-185 °C (dec.)(lit.)
storage temp.	Store below +30°C.
solubility	Chloroform (Slightly, Heated), Methanol (Slightly), Water (Slightly)
form	Hygroscopic Crystalline Powder
color	White to beige
PH	4.5-5 (10g/l, H2O, 20℃)
Water Solubility	soluble
Sensitive	Hygroscopic
BRN	3684083
InChI	InChI=1S/C6H12ClNO.ClH/c7-1-2-8-3-5-9-6-4-8;/h1-6H2;1H
CAS DataBase Reference	3647-69-6(CAS DataBase Reference)
EPA Substance Registry System	Morpholine, 4-(2-chloroethyl)-, hydrochloride (3647-69-6)

Safety information for 4-(2-Chloroethyl)morpholine hydrochloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06
GHS Hazard Statements	H301:Acute toxicity,oral H312:Acute toxicity,dermal H314:Skin corrosion/irritation H317:Sensitisation, Skin H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.