Moroxydine hydrochloride
Synonym(s):N-(Aminoiminomethyl)-4-morpholinecarboximidamide hydrochloride
- CAS NO.:3160-91-6
- Empirical Formula: C6H14ClN5O
- Molecular Weight: 207.66
- MDL number: MFCD00012798
- EINECS: 221-612-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is Moroxydine hydrochloride?
Originator
Grippe,Nissin
The Uses of Moroxydine hydrochloride
Moroxydine hydrochloride is an antiviral used against a number of RNA and DNA viruses.
The Uses of Moroxydine hydrochloride
Moroxydine is an antiviral used against a number of RNA and DNA viruses.
What are the applications of Application
Moroxydine hydrochloride is an antiviral
Manufacturing Process
43.5 g morpholine, 41.7 ml concentrated hydrochloric acid, 40 ml of water,
and 42 g dicyandiamide are refluxed for 48 hours, whereupon the reaction
mixture is cooled to +5°C and filtered. The filtrate is evaporated to dryness
and extracted and extracted with boiling ethanol. Yield: 50 g. The formed 4-
morpholinecarboximidoylguanidine hydrochloride is purified by recrystallization
from methanol. The salt may be converted into the base by adding equivalent
of any basic compound (triethylamine, sodium bicarbonate and so on).
In practice it is usually used as hydrochloride.
Therapeutic Function
Antiviral
General Description
Determination of moroxydine hydrochloride in Gan Mao Qing capsules by derivative spectrophotometric signal multiplier method has been reported. Therapeutical efficiency of moroxidine hydrochloride against herpes virus induced keratoconjunctivitis has been evaluated by immunofluorescence techniques.
Properties of Moroxydine hydrochloride
Melting point: | 211-214 °C(lit.) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | DMSO (Very Slightly, Heated), Water (Slightly) |
form | Solid |
color | Off-White |
Merck | 14,6272 |
Safety information for Moroxydine hydrochloride
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Moroxydine hydrochloride
InChIKey | FXYZDFSNBBOHTA-UHFFFAOYSA-N |
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