(3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
- CAS NO.：63038-10-8
- Empirical Formula: C12H16O2
- Molecular Weight: 192.26
- MDL number: MFCD16660665
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:00
What is (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one?
Description
Senkyunolide A is a phthalide originally isolated from celery seed essential oil that has cytoprotective and antiproliferative activities. It protects against cell injury induced by corticosterone in PC12 cells in a time-dependent manner when used at concentrations ranging from 0.125 to 0.5 mg/ml and reduces corticosterone-induced apoptosis at a concentration of 0.5 mg/ml. It also reverses increases in protein levels of phosphatase 2A (PP2A) and α-synuclein and reverses decreases in the phosphorylated forms of PP2A and α-synuclein. Senkyunolide A inhibits cell proliferation of HT-29 colon cancer (IC50 = 54.17 μM) but not non-cancerous human CCD-18Co colon cells (IC50 = 109.11 μM).
Definition
ChEBI: Senkyunolide is a member of 2-benzofurans.
Properties of (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
| storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
| solubility | DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
| form | Liquid |
| color | Colorless to light yellow |
Safety information for (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
Computed Descriptors for (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B 2,2-diethoxyethanethioamide Tubulysin H Tubulysin C (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Calcium Sodium Phosphosilicate IH Fuel shell 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-(2,4-Dibutoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane Methyl 4-amino-3-(piperidin-1-yl)benzoate 1-(4-Aminophenyl)-3-morpholino-5,6-dihydropyridin-2(1H)-one 4-(Azidomethyl)-3-chloropyridine 4,8-dibromo-5H-[1,2,3]triazolo[4',5':4,5]benzo[1,2-c][1,2,5]thiadiazole 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 4-bromo-7H-pyrrolo[2,3-d]pyrimidine 5-bromo-3-iodopyridin-2-ol 5-Bromo-4,6-difluoro-2,3-dihydro-1h-indole 3-HYDROXY-8-FLUORONAPHTHALENE-1-BORONIC ACID PINACOL ESTERRelated products of tetrahydrofuran
You may like
-
![3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione](https://img.chemicalbook.in//ProductImageIndia/2024-09/Raw/54575d9a-6e8e-412f-ab6d-3557d5ed92e3.jpg)
3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dioneView Details
952145-70-9 -
1262243-12-8View Details
1262243-12-8 -
Rimegepant Impurity 3View Details -
Sidchem 730View Details -
Sidchem BT 20View Details -
1572177-89-9View Details
1572177-89-9 -
6390-09-6View Details
6390-09-6 -
6-Bromo indoleView Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.