(3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
- CAS NO.:63038-10-8
- Empirical Formula: C12H16O2
- Molecular Weight: 192.26
- MDL number: MFCD16660665
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-13 11:39:26
What is (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one?
Description
Senkyunolide A is a phthalide originally isolated from celery seed essential oil that has cytoprotective and antiproliferative activities. It protects against cell injury induced by corticosterone in PC12 cells in a time-dependent manner when used at concentrations ranging from 0.125 to 0.5 mg/ml and reduces corticosterone-induced apoptosis at a concentration of 0.5 mg/ml. It also reverses increases in protein levels of phosphatase 2A (PP2A) and α-synuclein and reverses decreases in the phosphorylated forms of PP2A and α-synuclein. Senkyunolide A inhibits cell proliferation of HT-29 colon cancer (IC50 = 54.17 μM) but not non-cancerous human CCD-18Co colon cells (IC50 = 109.11 μM).
Definition
ChEBI: Senkyunolide is a member of 2-benzofurans.
Properties of (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | DMF: 5 mg/ml; DMSO: 5 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
form | Liquid |
color | Colorless to light yellow |
Safety information for (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
Computed Descriptors for (3S)-3β-Butyl-1,3,4,5-tetrahydroisobenzofuran-1-one
New Products
(R)-3-Aminobutanenitrile Hydrochloride 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION SODIUM VALPROATE Diclofenac Sodium Methylcobalamin (vitamin B12) VILDAGLIPTIN ACICLOVIR AMOXICILLIN (AMOXYCILLIN) TRIHYDRATE Desloratidine Related compound B Folic Acid Impurity G Glycopyrronium Bromide EP Impurity I Eltrombopag N-Oxide Impurity Di-Nitroso Acyclovir Impurity K DLRD N-OxideRelated products of tetrahydrofuran
You may like
-
88150-47-4 99%View Details
88150-47-4 -
VILDAGLIPTIN 274901-16-5 99%View Details
274901-16-5 -
177-11-7 1,4-Dioxa-8-azaspiro[4.5]decane 98+View Details
177-11-7 -
217299-03-1 98+View Details
217299-03-1 -
(R)-3-Aminobutanenitrile Hydrochloride 98+View Details
1073666-55-3 -
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 39124-20-4 98+View Details
39124-20-4 -
2006278-26-6 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride 98+View Details
2006278-26-6 -
39856-50-3 98+View Details
39856-50-3