3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOCYANATE

CAS NO.：16588-74-2
Empirical Formula: C9H3F6NO
Molecular Weight: 255.12
MDL number: MFCD00013559
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOCYANATE?

Chemical properties

clear colorless liquid

The Uses of 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOCYANATE

3,5-Bis(trifluoromethyl)phenyl isocyanate is used in Chemical derivatization of amino-functionalized model surfaces. Preparation of arylaminothiocarbonylpyridinium zwitterionic salts, via an exothermic reaction with 4-pyrrolidinopyridine. Synthesis of (S)-3-hydroxymethyl-2-methoxymethoxy-2?-(3-(3,5-bis(trifluoromethyl)phenyl)uryl-benzyl)-1,10-binaphthalene. Synthesis of 1-[3,5-bis(trifluoromethyl) phenyl]-3-(2-pyridyl)thiourea, via reaction with 2-amino pyridine in MeCN.

The Uses of 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOCYANATE

3,5-Bis(trifluoromethyl)phenyl isocyanate may be used in following studies:

Chemical derivatization of amino-functionalized model surfaces.
Preparation of arylaminothiocarbonylpyridinium zwitterionic salts, via an exothermic reaction with 4-pyrrolidinopyridine.
Synthesis of (S)-3-hydroxymethyl-2-methoxymethoxy-2′-(3-(3,5-bis(trifluoromethyl)phenyl)uryl-benzyl)-1,10-binaphthalene.
Synthesis of 1-[3,5-bis(trifluoromethyl) phenyl]-3-(2-pyridyl)thiourea, via reaction with 2-amino pyridine in MeCN.

What are the applications of Application

3,5-Bis(trifluoromethyl)phenyl isocyanate is used for the chemical derivatization of amino-functionalized model surfaces

Properties of 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOCYANATE

Boiling point:	62 °C (2 mmHg)
Density	1.476 g/mL at 25 °C (lit.)
refractive index	n20/D 1.43(lit.)
Flash point:	154 °F
form	Liquid
color	Clear colorless
Water Solubility	Hydrolyzes with water.
Sensitive	Moisture Sensitive
BRN	542272
CAS DataBase Reference	16588-74-2(CAS DataBase Reference)

Safety information for 3,5-BIS(TRIFLUOROMETHYL)PHENYL ISOCYANATE

Signal word	Danger
Pictogram(s)	Exclamation Mark Irritant GHS07 Health Hazard GHS08
GHS Hazard Statements	H315:Skin corrosion/irritation H317:Sensitisation, Skin H319:Serious eye damage/eye irritation H334:Sensitisation, respiratory H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.