3-(Trifluoromethyl)phenyl isocyanate
Synonym(s):α,α,α-Trifluoro-m-tolyl isocyanate
- CAS NO.：329-01-1
- Empirical Formula: C8H4F3NO
- Molecular Weight: 187.12
- MDL number: MFCD00002020
- EINECS: 206-341-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is 3-(Trifluoromethyl)phenyl isocyanate?
Chemical properties
colorless to light yellow liquid
The Uses of 3-(Trifluoromethyl)phenyl isocyanate
3-?(Trifluoromethyl)?phenyl Isocyanate is a reagent used in the synthesis of heme-regulated inhibitor as selective activators of the eukaryotic inhibition factor Alpha (eIF2α) phosphorylation arm of the endoplasmic reticulum stress response. Influences cell proliferation, cell differentiaton and adaptation to stress. Also a reagent in the preparation of sorafenib derivatives.
Flammability and Explosibility
Not classified
Safety Profile
Moderately toxic by ingestion, inhalation, and intraperitoneal routes. A lachrymator. Flammable liquid when exposed to heat, sparks, or flame. When heated to decomposition it emits very toxic fumes of NOx and F-. See also ISOCYANATES and FLUORIDES.
Properties of 3-(Trifluoromethyl)phenyl isocyanate
| Melting point: | -26 °C |
| Boiling point: | 54 °C11 mm Hg(lit.) |
| Density | 1.359 g/mL at 25 °C(lit.) |
| vapor pressure | 2.44 psi ( 20 °C) |
| refractive index | n |
| Flash point: | 138 °F |
| storage temp. | Keep Cold |
| solubility | soluble in Toluene |
| form | clear liquid |
| Specific Gravity | 1.359 |
| color | Colorless to Almost colorless |
| Water Solubility | 5.46g/L at 25℃ |
| Sensitive | Lachrymatory |
| BRN | 744880 |
| CAS DataBase Reference | 329-01-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Benzene, 1-isocyanato-3-(trifluoromethyl)-(329-01-1) |
| EPA Substance Registry System | 3-Trifluoromethylphenyl isocyanate (329-01-1) |
Safety information for 3-(Trifluoromethyl)phenyl isocyanate
| Signal word | Danger |
| Pictogram(s) |
 Flame Flammables GHS02  Corrosion Corrosives GHS05  Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H226:Flammable liquids H302:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H330:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 3-(Trifluoromethyl)phenyl isocyanate
New Products
Bromine 99.5% AR (4 x 500ml) Fehling's Solution No. B Amino Acid Kit of 23 items set Ammonium Molybdate Reagent Solution Beam's Reagent Solution Ehrlich's Reagent For detection of urobillinogen Sodium Amino Salicylate Dihydrate (PAS Sodium) IP/BP/USP/EP 1,2,3,4-Tetrahydrocarbazol-4-one 4-Hydroxy Carbazole Amino Salicylic Acid. U.S.P. 2 – Methoxy – 5- Sulfamoyl Benzoic acid Acetone Isobutryl oxime ester Curcuma aromatica Oil Curry leaf Extract Terminalia bellirica Extract Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract Ethyl 3-(Pyridin-2-Ylamino)Propanoate Bilastine -IP/BP/ Cypermethric Acid Chloride 5-Nitrosalicylaldehyde 5-(Difluoromethoxy)-2-Mercapto-1H-Benzimidazole- IP/BP/ Methyl Di Chloride (Mdc)Related products of tetrahydrofuran
You may like
-
3-(Trifluoromethyl)phenyl isocyanate CAS 329-01-1View Details
329-01-1 -
3-(Trifluoromethyl)phenyl Isocyanate CAS 329-01-1View Details
329-01-1 -
3-TRIFLUOROMETHYLPHENYL ISOCYANATE CAS 329-01-1View Details
329-01-1 -
7726-95-6 Bromine 99.5% AR (4 x 500ml) 99%View Details
7726-95-6 -
Formamide 99%View Details
75-12-7 -
85-81-4 6-Methoxy-8-Nitroquinoline 99%View Details
85-81-4 -
3-Bromo-4,5-Dihydro-1H-Benzo[B]Azepin-2(3H)-One 99%View Details
86499-96-9 -
(−)-Dip-Chloride 85116-37-6 99%View Details
85116-37-6
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.