Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

Synonym(s):Di(N-succinimidyl) 3,3′-dithiodipropionate;Dithiobis(succinimidyl propionate);DTSP;Lomant’s reagent

  • CAS NO.:57757-57-0
  • Empirical Formula: C14H16N2O8S2
  • Molecular Weight: 404.42
  • MDL number: MFCD00042045
  • EINECS: 260-931-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 09:03:02
3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester) Structural

What is 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)?

Description

DSP Crosslinker is a cleavable crosslinker. It contains two terminal NHS ester moieties which can react with primary amines. The disulfide bonds can be cleaved via a reduction reaction using Dithiothreitol (DTT) reagent.

Chemical properties

Off-White Solid

The Uses of 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester) can be used in the crosslinking of intracellular proteins prior to cell lysis.

The Uses of 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester) can be used as amine reactive homobifunctional cross-linking reagent, cleavable under mild conditions with hydroxylamine (pH 8.5, 3-6 h, 37oC)

The Uses of 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) has been used as a protein cross-linker.

What are the applications of Application

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) is a cleavable disulfide linkage-containing homobifunctional cross-linking reagent

General Description

3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) (DSP) is a homobifunctional cross-linking reagent containing a cleavable disulfide linkage. It is typically coupled to molecules containing primary amines by amide bonds buffered at pH 7.5 (6.5-8.5).

Properties of 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

Melting point: 128-133 °C
Boiling point: 560.1±60.0 °C(Predicted)
Density  1.57±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  chloroform: 50 mg/mL
form  powder
color  Off-White
BRN  1518074
CAS DataBase Reference 57757-57-0(CAS DataBase Reference)

Safety information for 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3,3`-Dithiobispropanoic acid bis(N-hydroxysucciniMde ester)

Related products of tetrahydrofuran

You may like

  • Di(n-succinimidyl) 3,3'-dithiodipropionate 97% CAS 57757-57-0
    Di(n-succinimidyl) 3,3'-dithiodipropionate 97% CAS 57757-57-0
    57757-57-0
    View Details
  • Di(N-succinimidyl) 3,3'-Dithiodipropionate [Cross-linking Reagent] CAS 57757-57-0
    Di(N-succinimidyl) 3,3'-Dithiodipropionate [Cross-linking Reagent] CAS 57757-57-0
    57757-57-0
    View Details
  • 3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) CAS 57757-57-0
    3,3′-Dithiodipropionic acid di(N-hydroxysuccinimide ester) CAS 57757-57-0
    57757-57-0
    View Details
  • Dechloro Desloratadine
    Dechloro Desloratadine
    View Details
  • Dehydro Desloratadine
    Dehydro Desloratadine
    View Details
  • Edoxaban Impurity 57
    Edoxaban Impurity 57
    2089454-69-1
    View Details
  • Empagliflozin Bromo Impurity
    Empagliflozin Bromo Impurity
    View Details
  • Ipratropium EP Impurity B
    Ipratropium EP Impurity B
    58073-59-9
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.