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HomeProduct name list3-(N-Methylamino)-L-alanine

3-(N-Methylamino)-L-alanine

3-(N-Methylamino)-L-alanine Structural

What is 3-(N-Methylamino)-L-alanine?

Definition

ChEBI: A non-proteinogenic L-alpha-amino acid that is L-alanine in which one of the methyl hydrogens is replaced by a methylamino group. A non-proteinogenic amino acid produced by cyanobacteria, it is a neurotoxi that has been postulated as a possible cause of neurodegenerative disorders of aging such as Alzheimer's disease, amyotrophic lateral sclerosis, and the amyotrophic lateral sclerosis/parkinsonism-dementia complex (ALS-PDC) syndrome of Guam.

Biological Activity

Neurotoxic glutamate agonist originally isolated from Cycas circinalis. Implicated in the pathogenesis of amyotrophic lateral sclerosis-Parkinsonism-dementia complex of Guam (Guam ALS-PD).

Properties of 3-(N-Methylamino)-L-alanine

Boiling point: 284.2±30.0 °C(Predicted)
Density  1.157±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  H2O: solutions may be stored for several days at 4°Csoluble
pka 1.88±0.10(Predicted)
form  solid
color  white
EPA Substance Registry System L-Alanine, 3-(methylamino)- (15920-93-1)

Safety information for 3-(N-Methylamino)-L-alanine

Computed Descriptors for 3-(N-Methylamino)-L-alanine

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