3-Maleimidobenzoic acid N-hydroxysuccinimide ester
Synonym(s):MBS
- CAS NO.：58626-38-3
- Empirical Formula: C15H10N2O6
- Molecular Weight: 314.25
- MDL number: MFCD00005514
- EINECS: 261-368-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is 3-Maleimidobenzoic acid N-hydroxysuccinimide ester?
Description
MBS is a heterobifunction crosslinker that contains a maleimide group which is reactive towards sulfhydryls and an NHS ester, useful for targeting amine groups.
Chemical properties
Crystalline
The Uses of 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
3-Maleimidobenzoic acid N-hydroxysuccinimide ester is a heterobifunctional coupling reagent useful for forming enzyme immunoconjugates. The reactive groups are the NHS ester and maeimide.
The Uses of 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
N-Succinimidyl 3-maleimidobenzoate is useful for forming enzyme immunoconjugates. It has a 9.9 Angstrom spacer arm. Heterobifunctional crosslinking reagent reactive toward primary amine and sulfhydryl. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates
What are the applications of Application
3-N-Maleimidobenzoic Acid N-Succinimidyl Ester is a heterobifunctional amine- and sulfhydryl-reactive crosslinker, 9.9 Angstrom spacer arm
Biochem/physiol Actions
3-Maleimidobenzoic acid N-hydroxysuccinimide is used as a fixative for the preservation of pollen tube F-actin distribution. It imposes less damage when used on pollen tubes.
Properties of 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
| Melting point: | 175-177 °C(lit.) |
| Boiling point: | 524.5±52.0 °C(Predicted) |
| Density | 1.59±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | ethyl acetate or DMF: ≤20 mg/mL may require addition of solvent to coupling buffer to at least 5% to maintain solubility |
| pka | -2.63±0.20(Predicted) |
| form | crystalline |
| color | White to Almost white |
| Sensitive | Moisture & Light Sensitive |
| BRN | 1505254 |
| CAS DataBase Reference | 58626-38-3(CAS DataBase Reference) |
Safety information for 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 3-Maleimidobenzoic acid N-hydroxysuccinimide ester
| InChIKey | LLXVXPPXELIDGQ-UHFFFAOYSA-N |
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