3-Chloro-4-hydroxyaniline

Synonym(s):3-Chloro-4-hydroxyaniline

CAS NO.：3964-52-1
Empirical Formula: C6H6ClNO
Molecular Weight: 143.57
MDL number: MFCD00128891
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 3-Chloro-4-hydroxyaniline?

Chemical properties

solid

The Uses of 3-Chloro-4-hydroxyaniline

4-Amino-2-chlorophenol may be used in the synthesis of the following compounds:

N-(3-chloro-4-hydroxyphenyl)-N′,N′-dimethylurea
1,4-diketo-3-((4-[N-(3-chloro-4-hydroxyphenyl)amino]sulfonyl)phenyl)-6-phenylpyrrolo[3,4-c]pyrrole, a novel fluorescent pH-indicator
4-(4-aminophenoxy)-N-(4-(4-aminophenoxy) benzylidene)-3-chloroaniline
4-(4-amino-3-methylphenoxy)-N-(4-(4-amino-3-methylphenoxy)benzylidene)-3-chloroaniline
4-(4-amino-2-methylphenoxy)-N-(4-(4-amino-2-methylphenoxy)benzylidene)-3-chloroaniline

General Description

4-Amino-2-chlorophenol (4A2CP) is a chlorinated aniline. Nephrotoxic potential of 4-amino-2-chlorophenol and its comparison with 4-aminophenol, 4-amino-2-chlorophenol, 4-amino-3-chlorophenol and 4-amino-2,6-dichlorophenol using isolated renal cortical cells from male Fischer 344 rats has been investigated.

Properties of 3-Chloro-4-hydroxyaniline

Melting point:	150-153 °C(lit.)
Boiling point:	292.7±25.0 °C(Predicted)
Density	1.406±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	8.75±0.18(Predicted)
color	Dark Brown
Stability:	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	3964-52-1(CAS DataBase Reference)

Safety information for 3-Chloro-4-hydroxyaniline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.