2-Chloro-5-aminophenol
- CAS NO.：6358-06-1
- Empirical Formula: C6H6ClNO
- Molecular Weight: 143.57
- MDL number: MFCD01707858
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is 2-Chloro-5-aminophenol?
Chemical properties
White powder
The Uses of 2-Chloro-5-aminophenol
5-Amino-2-chlorophenol is used in the synthesis of antimalarial quinolones. Also used in the synthesis of potent anti-HIV agents based upon pyrimidinylphenylamine 1.
Properties of 2-Chloro-5-aminophenol
| Melting point: | 160 °C |
| Boiling point: | 185.5°C (rough estimate) |
| Density | 1.2028 (rough estimate) |
| refractive index | 1.5618 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO, Methanol |
| form | Powder |
| pka | 8.55±0.10(Predicted) |
| color | Gray |
| Sensitive | Light Sensitive |
| CAS DataBase Reference | 6358-06-1(CAS DataBase Reference) |
| EPA Substance Registry System | Phenol, 5-amino-2-chloro- (6358-06-1) |
Safety information for 2-Chloro-5-aminophenol
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H312:Acute toxicity,dermal H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
Computed Descriptors for 2-Chloro-5-aminophenol
| InChIKey | JSCNCRWPXOTDDZ-UHFFFAOYSA-N |
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