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HomeProduct name list3-Amino-2(1H)-pyridinone

3-Amino-2(1H)-pyridinone

3-Amino-2(1H)-pyridinone Structural

What is 3-Amino-2(1H)-pyridinone?

Chemical properties

Brown to off-white crystalline powder.

The Uses of 3-Amino-2(1H)-pyridinone

It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

Properties of 3-Amino-2(1H)-pyridinone

Melting point: 118-130 °C
Boiling point: 206.4°C (rough estimate)
Density  1.2111 (rough estimate)
refractive index  1.4800 (estimate)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
form  Powder
pka 13.87±0.10(Predicted)
color  Dark brown to black
Water Solubility  Slightly soluble in water.
CAS DataBase Reference 33630-99-8(CAS DataBase Reference)

Safety information for 3-Amino-2(1H)-pyridinone

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 3-Amino-2(1H)-pyridinone

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