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HomeProduct name list3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

Synonym(s):3-(2-Furanylmethyl)-3,7-dihydro-1,8-dimethyl-1H-purine-2,6-dione

  • CAS NO.:80288-49-9
  • Empirical Formula: C12H12N4O3
  • Molecular Weight: 260.25
  • MDL number: MFCD00153799
  • EINECS: 200-158-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE Structural

What is 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE?

The Uses of 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

inhibitor

The Uses of 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

Furafylline is a selective inhibitor of human cytochrome P450. It is also reported to inhibit the oxidation of caffeine.

What are the applications of Application

Furafylline is an inhibitor of Cytochrome P450 (CYP1A2) and phosphodiesterase (PDE)

Definition

ChEBI: Furafylline is an oxopurine.

Biochem/physiol Actions

Furafylline (1,8-dimethyl-3-(2′ -furfuryl)methylxanthine) is a xanthine derivative. It is preferred in treating asthma. It serves as a N3-demethylation inhibitor of caffeine. Furafylline does not show much effect on human monooxygenase activities. It is considered as an efficient bronchodilator and as an inhibitor of anaphylactic reactions, when compared to theophylline.

Properties of 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

Melting point: >162°C (dec.)
Boiling point: 543.6±60.0 °C(Predicted)
Density  1.443±0.06 g/cm3(Predicted)
storage temp.  2-8°C(protect from light)
solubility  ethanol: 0.33 mg/mL
form  solid
pka 8.62±0.70(Predicted)
color  white

Safety information for 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

Computed Descriptors for 3-(2-FURANYLMETHYL)-3,7-DIHYDRO-1,8-DIMETHYL-1H-PURINE-2,6-DIONE

InChIKey KGQZGCIVHYLPBH-UHFFFAOYSA-N

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