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HomeProduct name listDMT-dC(ac) Phosphoramidite

DMT-dC(ac) Phosphoramidite

Synonym(s):DMT-dC(ac) Amidite;N4-Acetyl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxycytidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite];N-acetyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

  • CAS NO.:154110-40-4
  • Empirical Formula: C41H50N5O8P
  • Molecular Weight: 771.84
  • MDL number: MFCD09842112
  • EINECS: 2017-001-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-12-13 09:07:48
DMT-dC(ac) Phosphoramidite  Structural

What is DMT-dC(ac) Phosphoramidite ?

Chemical properties

White or off-white power

The Uses of DMT-dC(ac) Phosphoramidite

Ac-dC phosphoramidite is a nucleoside used in the preparation of cytidine-?based nucleotide-?lipids which can act as supramolecular gelators depending on both the nucleobase and the presence of salts.

Definition

5'-O-DMT-N4-Acetyl-2'-Deoxycytidine-CE phosphoramidite (DMT-dC(ac) Phosphoramidite) is a cytidine phosphoramidite monomer that can be applied to make oligodeoxynucleotides.

storage

-20°C, protect from light, stored under nitrogen. In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen).

Properties of DMT-dC(ac) Phosphoramidite

storage temp.  -20°C
solubility  DMSO : 100 mg/mL (129.56 mM; Need ultrasonic)
form  powder
pka 10.26±0.20(Predicted)
color  white to off-white

Safety information for DMT-dC(ac) Phosphoramidite

Computed Descriptors for DMT-dC(ac) Phosphoramidite

InChIKey MECWEBCHRKVTNV-QQIWIMIASA-N
SMILES O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C=CC(NC(C)=O)=NC2=O)C[C@@H]1OP(N(C(C)C)C(C)C)OCCC#N |&1:25,27,40,r|

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