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HomeProduct name listDMT-dG(ib) Phosphoramidite

DMT-dG(ib) Phosphoramidite

Synonym(s):DMT-dG(ib) amidite;DMT-dG(ib) Phosphoramidite;Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-N-(2-methyl-1-oxopropyl)-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyguanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

  • CAS NO.:93183-15-4
  • Empirical Formula: C44H54N7O8P
  • Molecular Weight: 839.92
  • MDL number: MFCD00055147
  • EINECS: 685-519-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-12-13 11:46:43
DMT-dG(ib) Phosphoramidite Structural

What is DMT-dG(ib) Phosphoramidite?

The Uses of DMT-dG(ib) Phosphoramidite

2’-Deoxy-5’-O-DMT-N2-isobutyrylguanosine 3’-CE Phosphoramidite is used to prepare antisense oligonucleotides containing conformationally constrained methoxyaminomethylene and aminooxymethylene and aminomethylene bridged nucleoside analogs.

Definition

5'-O-DMT-N2-Isobutyryl-2'-Deoxyguanosine-CE Phosphoramidite (DMT-dG(ib) Phosphoramidite) is a nucleoside phosphoramidite that contains an isobutyryl group, and it can be used in the synthesis of oligonucleotides.

storage

-20°C, stored under nitrogen.
In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Properties of DMT-dG(ib) Phosphoramidite

Density  1.22 at 20℃
vapor pressure  0-0Pa at 20-50℃
storage temp.  Sealed in dry,2-8°C
solubility  soluble, clear
form  powder or granules
pka 9.16±0.20(Predicted)
color  white to off-white

Safety information for DMT-dG(ib) Phosphoramidite

Computed Descriptors for DMT-dG(ib) Phosphoramidite

InChIKey FDRMKYVTIFSDPR-MMROLVBFSA-N
SMILES C(OC[C@H]1O[C@@H](N2C=NC3C(=O)NC(NC(=O)C(C)C)=NC2=3)C[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C)(C1=CC=CC=C1)(C1=CC=C(OC)C=C1)C1=CC=C(OC)C=C1 |&1:3,5,23,r|

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