DMT-dG(dmf) Phosphoramidite

Synonym(s):DMT-dG(dmf) Amidite;N-[(dimethylamino)methylene]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxyguanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite];N2-Dimethylformamidine-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

CAS NO.：330628-04-1
Empirical Formula: C43H53N8O7P
Molecular Weight: 824.9
MDL number: MFCD09842106
EINECS: 2017-001-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-12-13 09:16:16

What is DMT-dG(dmf) Phosphoramidite?

Chemical properties

White or off-white power

The Uses of DMT-dG(dmf) Phosphoramidite

Dmf-dG-CE phosphoramidite is a nucleotide and guanosine (G837895) derivative used in the preparation of synthetic RNA fragments, and other macromolecules such as micellar thrombin-binding aptamers as anticoagulants.

Definition

5'-O-DMT-2'-Deoxyguanosine(DMF)-CE Phosphoramidite, or DMT-dG(dmf) Phosphoramidite, is a nucleoside amidite analog comprised of 2'-deoxy-N2,5'-O-dimethoxytrityl guanosine (DMF) and 5'-O-dimethoxytrityl cytidine monophosphate (DMT).

Properties of DMT-dG(dmf) Phosphoramidite

Boiling point:	876.3±75.0 °C(Predicted)
storage temp.	Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO : 100 mg/mL (121.23 mM; Need ultrasonic)
pka	3.80±0.20(Predicted)
form	powder
color	white to off-white

Safety information for DMT-dG(dmf) Phosphoramidite

Computed Descriptors for DMT-dG(dmf) Phosphoramidite

InChIKey	YRQAXTCBMPFGAN-UNHDIWNRSA-N
SMILES	C12N=C(/N=C/N(C)C)NC(=O)C=1N=CN2[C@H]1C[C@@H]([C@@H](COC(C2C=CC=CC=2)(C2C=CC(OC)=CC=2)C2=CC=C(C=C2)OC)O1)OP(OCCC#N)N(C(C)C)C(C)C \|&1:15,17,18,r\|