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HomeProduct name list(2R)-(-)-Glycidyl tosylate

(2R)-(-)-Glycidyl tosylate

Synonym(s):(R)-(−)-Glycidyl p-toluenesulfonate;(R)-(−)-Glycidyl tosylate;(R)-(−)-Oxirane-2-methanol p-toluenesulfonate salt

  • CAS NO.:113826-06-5
  • Empirical Formula: C10H12O4S
  • Molecular Weight: 228.26
  • MDL number: MFCD00010834
  • EINECS: 601-283-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-28 18:20:31
(2R)-(-)-Glycidyl tosylate Structural

What is (2R)-(-)-Glycidyl tosylate?

Chemical properties

white crystalline powder

The Uses of (2R)-(-)-Glycidyl tosylate

Protected Glycidol, (2R)-(-)-Glycidyl tosylate is used as an intermediate in the preparation of neurochemicals.

The Uses of (2R)-(-)-Glycidyl tosylate

(2R)-(-)-Glycidyl Tosylate is a protected glycidol used as an intermediate in the preparation of neurochemicals.

The Uses of (2R)-(-)-Glycidyl tosylate

(2R)-(-)-Glycidyl tosylate may be used to prepare:

  • 1-O-hexadecyl-sn-glycerol 3-O-p-toluenesulfonate by reacting with 1-hexadecanol in the presence of boron trifluoride etherate.
  • 4-Oxiranylmethoxy-(1H)-indole by reacting with 4-hydroxyindole in the presence of sodium hydride.
  • [18F]Epifluorohydin, an intermediate for preparing of [18F]fluoromisonidazole.
It can also be used as a starting material in the synthesis of 1,2-diacyl-sn-3-glycerophosphocholines.

Properties of (2R)-(-)-Glycidyl tosylate

Melting point: 46-49 °C(lit.)
Boiling point: 340.07°C (rough estimate)
alpha  -18 º (c=2.5,CHCl3)
Density  1.3749 (rough estimate)
refractive index  1.5400 (estimate)
Flash point: >230 °F
storage temp.  2-8°C
solubility  dioxane: 50 mg/mL, clear
form  powder
color  yellow to orange
Water Solubility  decomposes
BRN  3592142
CAS DataBase Reference 113826-06-5(CAS DataBase Reference)

Safety information for (2R)-(-)-Glycidyl tosylate

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H317:Sensitisation, Skin
H318:Serious eye damage/eye irritation
H341:Germ cell mutagenicity
H350:Carcinogenicity
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P201:Obtain special instructions before use.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for (2R)-(-)-Glycidyl tosylate

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