(2R)-(-)-Glycidyl tosylate

Synonym(s):(R)-(−)-Glycidyl p-toluenesulfonate;(R)-(−)-Glycidyl tosylate;(R)-(−)-Oxirane-2-methanol p-toluenesulfonate salt

white crystalline powder

Protected Glycidol, (2R)-(-)-Glycidyl tosylate is used as an intermediate in the preparation of neurochemicals.

(2R)-(-)-Glycidyl Tosylate is a protected glycidol used as an intermediate in the preparation of neurochemicals.

(2R)-(-)-Glycidyl tosylate may be used to prepare:

1-O-hexadecyl-sn-glycerol 3-O-p-toluenesulfonate by reacting with 1-hexadecanol in the presence of boron trifluoride etherate.
4-Oxiranylmethoxy-(1H)-indole by reacting with 4-hydroxyindole in the presence of sodium hydride.
[¹⁸F]Epifluorohydin, an intermediate for preparing of [¹⁸F]fluoromisonidazole.

It can also be used as a starting material in the synthesis of 1,2-diacyl-sn-3-glycerophosphocholines.

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H317:Sensitisation, Skin H318:Serious eye damage/eye irritation H341:Germ cell mutagenicity H350:Carcinogenicity H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P201:Obtain special instructions before use. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P308+P313:IF exposed or concerned: Get medical advice/attention.