(2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE
- CAS NO.：106268-96-6
- Empirical Formula: C11H11NO5
- Molecular Weight: 237.21
- MDL number: MFCD00012315
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
What is (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE?
The Uses of (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE
(R)-(-)-2-Methylglycidyl 4-Nitrobenzoate is an intermediate in the synthesis of Delamanid (D230660), a novel anti-tuberculosis medication that inhibits mycolic acid synthesis and shows potent in-vitro and in-vivo activity against drug-resistant strains of Mycobacterium tuberculosis.
Properties of (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE
| Melting point: | 87-89 °C(lit.) |
| Boiling point: | 379.74°C (rough estimate) |
| Density | 1.3350 (rough estimate) |
| refractive index | 1.5300 (estimate) |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform, DCM |
| form | Solid |
| color | Light Yellow |
| optical activity | [α]19/D 5.9°, c = 2.4 in chloroform |
Safety information for (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (2R)-(-)-2-METHYLGLYCIDYL 4-NITROBENZOATE
New Products
3-(hexyloxy)-4-(pyridin-3-yl)-1,2,5-thiadiazole 3-Pyridineacetonitrile, α-hydroxy- 2-Propanamine, 1-chloro-, hydrochloride (9CI) 3-Iodophenylacetic acid Cyclohexane, (2-propynyloxy)- (S)-1-Boc-3-methanesulfonyloxy-pyrrolidine Pivalic anhydride,98% Phenylmethanesulfonyl fluoride, 98% Glyoxylic acid solution, 50% in water tert-Butyl glycinate,97% 4-Ethoxybenzoic acid, 99% Sodium 1-octanesulfonate monohydrate 7-Ethyl Tryptophol 2-AMINO-3,5-DIBROMO BENZALDEHYDE [ADBA] L-Glutamic Acid Dimethyl Ester Hcl N, N-Carbonyldiimidazole (CDI) 5-Cyanophthalide 10-Methoxy-5H-dibenz[b,f]azepine 3-Methoxybenzonitrile Dibenzoyl Peroxide 4-Methoxybenzonitrile Titanium Dioxide Chloral PentachlorobenzonitrileRelated products of tetrahydrofuran
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