2,6-Difluoropyridine
- CAS NO.：1513-65-1
- Empirical Formula: C5H3F2N
- Molecular Weight: 115.08
- MDL number: MFCD00006227
- EINECS: 216-152-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-01-22 16:43:48
What is 2,6-Difluoropyridine?
Chemical properties
Colorless to light yellow liquid
The Uses of 2,6-Difluoropyridine
2,6-Difluoropyridine has been used in the preparation of poly(pyridine ether)s via polycondensation with silylated 1,1,1-tris(4-hydroxyphenyl)ethane.
General Description
Lithium diisopropylamide (LDA)-mediated ortholithiations of 2,6-difluoropyridine in tetrahydrofuran at -78°C has been studied using a combination of IR and NMR spectroscopic and computational methods. Polycondensation of bistrimethylsilyl derivatives of various diphenols with 2,6-difluoropyridine in N-methylpyrrolidone in the presence of K2CO3 has been investigated.
Properties of 2,6-Difluoropyridine
| Boiling point: | 124.5 °C/743 mmHg (lit.) |
| Density | 1.268 g/mL at 25 °C (lit.) |
| refractive index | n |
| Flash point: | 93 °F |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Not miscible or difficult to mix. |
| form | Liquid |
| pka | -6.09±0.10(Predicted) |
| Specific Gravity | 1.268 |
| color | Clear purple-red |
| BRN | 1422549 |
| Dielectric constant | 107.8 |
| CAS DataBase Reference | 1513-65-1(CAS DataBase Reference) |
| NIST Chemistry Reference | 2,6-Difluoropyridine(1513-65-1) |
Safety information for 2,6-Difluoropyridine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,6-Difluoropyridine
| InChIKey | MBTGBRYMJKYYOE-UHFFFAOYSA-N |
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