2,6-Difluoropyridine
- CAS NO.:1513-65-1
- Empirical Formula: C5H3F2N
- Molecular Weight: 115.08
- MDL number: MFCD00006227
- EINECS: 216-152-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-01-22 16:43:48
What is 2,6-Difluoropyridine?
Chemical properties
Colorless to light yellow liquid
The Uses of 2,6-Difluoropyridine
2,6-Difluoropyridine has been used in the preparation of poly(pyridine ether)s via polycondensation with silylated 1,1,1-tris(4-hydroxyphenyl)ethane.
General Description
Lithium diisopropylamide (LDA)-mediated ortholithiations of 2,6-difluoropyridine in tetrahydrofuran at -78°C has been studied using a combination of IR and NMR spectroscopic and computational methods. Polycondensation of bistrimethylsilyl derivatives of various diphenols with 2,6-difluoropyridine in N-methylpyrrolidone in the presence of K2CO3 has been investigated.
Properties of 2,6-Difluoropyridine
Boiling point: | 124.5 °C/743 mmHg (lit.) |
Density | 1.268 g/mL at 25 °C (lit.) |
refractive index | n |
Flash point: | 93 °F |
storage temp. | Inert atmosphere,2-8°C |
solubility | Not miscible or difficult to mix. |
form | Liquid |
pka | -6.09±0.10(Predicted) |
Specific Gravity | 1.268 |
color | Clear purple-red |
BRN | 1422549 |
Dielectric constant | 107.8 |
CAS DataBase Reference | 1513-65-1(CAS DataBase Reference) |
NIST Chemistry Reference | 2,6-Difluoropyridine(1513-65-1) |
Safety information for 2,6-Difluoropyridine
Signal word | Warning |
Pictogram(s) |
Flame Flammables GHS02 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,6-Difluoropyridine
InChIKey | MBTGBRYMJKYYOE-UHFFFAOYSA-N |
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
2,3-DIFLUOROPYRIDINE
Flupirtine
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
2,5-Dimethylpyridine
3,5-DIFLUOROPYRIDINE
2,5-PYRIDINEDICARBOXYLIC ACID
2,6-Lutidine
2-Chloro-5-chloromethylpyridine
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