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HomeProduct name listFlupirtine

Flupirtine

  • CAS NO.:56995-20-1
  • Empirical Formula: C15H17FN4O2
  • Molecular Weight: 304.32
  • MDL number: MFCD00864265
  • EINECS: 260-503-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
Flupirtine Structural

What is Flupirtine?

The Uses of Flupirtine

Therapeutic use of Flupirtine was discontinued due to drug induced liver injury (DILI). Since the mechanism of action is not related to its adverse effects, it is important to focus on chemical modifications.

The Uses of Flupirtine

Analgesic.

Definition

ChEBI: N-[2-amino-6-[(4-fluorophenyl)methylamino]-3-pyridinyl]carbamic acid ethyl ester is an aminopyridine.

Clinical Use

Flupirtine maleate is an analgesic with an unknown mode of action. It is used in single doses of 100 mg orally and 150 mg rectally for the treatment of different pain conditions.

Properties of Flupirtine

Melting point: 115-116°
Boiling point: 445.15°C (rough estimate)
Density  1.350±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C
solubility  Soluble in DMSO
form  Powder
pka 12.19±0.70(Predicted)
Water Solubility  1g/L(temperature not stated)

Safety information for Flupirtine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H312:Acute toxicity,dermal
H332:Acute toxicity,inhalation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for Flupirtine

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