2,5-Dimethylaniline
Synonym(s):2,5-Xylidine;2-Amino-p-xylene;2-Amino-1,4-dimethylbenzene
- CAS NO.:95-78-3
- Empirical Formula: C8H11N
- Molecular Weight: 121.18
- MDL number: MFCD00007743
- EINECS: 202-451-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-17 21:30:02
What is 2,5-Dimethylaniline?
Chemical properties
clear yellow to red-brown liquid
The Uses of 2,5-Dimethylaniline
2,5-Dimethylaniline is widely used as raw materials to produce imaging chemicals like organic dyes and pigments. It is also used in the production of antioxidants, pharmaceutical, agricultural, rubber chemicals and other target organic molecules. 2,5-Dimethylaniline was also used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity. The Fourier transform infrared (FTIR) and Raman spectra of 2,5-dimethylaniline was studied5. It induced transcription of lccIV.
The Uses of 2,5-Dimethylaniline
The uses are the same as those of xylidines.
The Uses of 2,5-Dimethylaniline
2,5-Dimethylaniline was used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity.
Definition
ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 5-positions are replaced by methyl groups. It is used in the manufacture of dyes and other chemicals.
General Description
Dark brown liquid.
Air & Water Reactions
2,5-Dimethylaniline may be sensitive to prolonged exposure to air. Insoluble in water.
Reactivity Profile
2,5-Dimethylaniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.
Fire Hazard
2,5-Dimethylaniline is combustible.
Safety Profile
Suspected carcinogen. A poison. Moderately toxic by ingestion. Quesuonable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.
Purification Methods
Convert p-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry over KOH and fractionally distil. The acetyl derivative has m 142o (from H2O or toluene), and the benzoyl derivative has m 140o (from EtOH). [Beilstein 12 H 1135, 12 IV 2567.]
Properties of 2,5-Dimethylaniline
Melting point: | 11.5 °C(lit.) |
Boiling point: | 218 °C(lit.) |
Density | 0.973 g/mL at 25 °C(lit.) |
vapor pressure | 20Pa |
refractive index | n |
Flash point: | 201 °F |
storage temp. | Store below +30°C. |
solubility | Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sparingly) |
form | Liquid |
pka | pK1:4.53(+1) (25°C) |
color | Clear yellow to red-brown |
Water Solubility | <0.1 g/100 mL at 18 ºC |
Merck | 14,10084 |
BRN | 2205178 |
CAS DataBase Reference | 95-78-3(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenamine, 2,5-dimethyl-(95-78-3) |
IARC | 3 (Vol. 16, Sup 7) 1987 |
EPA Substance Registry System | 2,5-Dimethylaniline (95-78-3) |
Safety information for 2,5-Dimethylaniline
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09 |
GHS Hazard Statements |
H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for 2,5-Dimethylaniline
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Supreet Chemicals Pvt.Ltd.
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Yashasvi Rasayan Pvt Ltd
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