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HomeProduct name list2,5-Dimethylaniline

2,5-Dimethylaniline

Synonym(s):2,5-Xylidine;2-Amino-p-xylene;2-Amino-1,4-dimethylbenzene

  • CAS NO.:95-78-3
  • Empirical Formula: C8H11N
  • Molecular Weight: 121.18
  • MDL number: MFCD00007743
  • EINECS: 202-451-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:32
2,5-Dimethylaniline Structural

What is 2,5-Dimethylaniline?

Chemical properties

clear yellow to red-brown liquid

The Uses of 2,5-Dimethylaniline

2,5-Dimethylaniline is widely used as raw materials to produce imaging chemicals like organic dyes and pigments. It is also used in the production of antioxidants, pharmaceutical, agricultural, rubber chemicals and other target organic molecules. 2,5-Dimethylaniline was also used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity. The Fourier transform infrared (FTIR) and Raman spectra of 2,5-dimethylaniline was studied5. It induced transcription of lccIV.

The Uses of 2,5-Dimethylaniline

The uses are the same as those of xylidines.

The Uses of 2,5-Dimethylaniline

2,5-Dimethylaniline was used in the synthesis of nanocomposite of multi-walled carbon nanotubes embedded in poly(2,5-dimethylaniline). 2,5-Dimethylaniline was used to study the effect of metabolites formed from 2,5-xylidine by fungi on laccase activity.

Definition

ChEBI: A primary arylamine that is aniline in which the hydrogens at the 2- and 5-positions are replaced by methyl groups. It is used in the manufacture of dyes and other chemicals.

General Description

Dark brown liquid.

Air & Water Reactions

2,5-Dimethylaniline may be sensitive to prolonged exposure to air. Insoluble in water.

Reactivity Profile

2,5-Dimethylaniline ignites on contact with fuming nitric acid . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

2,5-Dimethylaniline is combustible.

Safety Profile

Suspected carcinogen. A poison. Moderately toxic by ingestion. Quesuonable carcinogen. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidme entries.

Purification Methods

Convert p-xylidine to a derivative (see below) which, after recrystallisation, is decomposed with alkali to give the free base. Dry over KOH and fractionally distil. The acetyl derivative has m 142o (from H2O or toluene), and the benzoyl derivative has m 140o (from EtOH). [Beilstein 12 H 1135, 12 IV 2567.]

Properties of 2,5-Dimethylaniline

Melting point: 11.5 °C(lit.)
Boiling point: 218 °C(lit.)
Density  0.973 g/mL at 25 °C(lit.)
vapor pressure  20Pa
refractive index  n20/D 1.559(lit.)
Flash point: 201 °F
storage temp.  Store below +30°C.
solubility  Chloroform (Slightly), Dichloromethane (Slightly), DMSO (Sparingly)
form  Liquid
pka pK1:4.53(+1) (25°C)
color  Clear yellow to red-brown
Water Solubility  <0.1 g/100 mL at 18 ºC
Merck  14,10084
BRN  2205178
CAS DataBase Reference 95-78-3(CAS DataBase Reference)
NIST Chemistry Reference Benzenamine, 2,5-dimethyl-(95-78-3)
IARC 3 (Vol. 16, Sup 7) 1987
EPA Substance Registry System 2,5-Dimethylaniline (95-78-3)

Safety information for 2,5-Dimethylaniline

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H373:Specific target organ toxicity, repeated exposure
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P314:Get medical advice/attention if you feel unwell.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for 2,5-Dimethylaniline

2,5-Dimethylaniline manufacturer

JSK Chemicals

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Supreet Chemicals Pvt.Ltd.

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ALS INDIA LIFE SCIENCES

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Yashasvi Rasayan Pvt Ltd

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ALPHA CHEMIKA

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Anand Agencies

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Phone:91-9075014125
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ASM Organics

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Phone:91-9866122393
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