Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list2,4,5-Trifluorobenzyl bromide

2,4,5-Trifluorobenzyl bromide

  • CAS NO.:157911-56-3
  • Empirical Formula: C7H4BrF3
  • Molecular Weight: 225.01
  • MDL number: MFCD00061209
  • EINECS: 642-693-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-24 19:19:26
2,4,5-Trifluorobenzyl bromide Structural

What is 2,4,5-Trifluorobenzyl bromide?

Chemical properties

White low melting solid

The Uses of 2,4,5-Trifluorobenzyl bromide

2,4,5-trifluorobenzyl bromide is an important intermediate in the synthesis of Ensitrelvir (S-217622). Ensitrelvir is the latest oral drug developed by Japan's Shionogi Pharmaceutical Company to treat COVID-19. It is the first orally active, non-covalent, non-peptide SARS-CoV-23CL protease inhibitor.

What are the applications of Application

2,4,5-TRIFLUOROBENZYL BROMIDE is a useful research chemical.

Synthesis

Preparing 2,4,5-Trifluorobenzyl bromide, involves (a) carrying out esterification reaction on 2,4,5-trifluorobenzyl chloride and carboxylate to prepare 2,4,5-trifluorobenzyl ester, (b) hydrolyzing 2,4,5-trifluorobenzyl ester to prepare 2,4,5-trifluorobenzyl alcohol, and (c) brominating 2,4,5-trifluorobenzyl alcohol to prepare target product.

Properties of 2,4,5-Trifluorobenzyl bromide

Boiling point: 188.8±35.0 °C(Predicted)
Density  1.71
refractive index  1.5015
storage temp.  Inert atmosphere,Room Temperature
form  clear liquid
color  Colorless to Light yellow
Specific Gravity 1.71
Sensitive  Lachrymatory
BRN  8312091
InChI InChI=1S/C7H4BrF3/c8-3-4-1-6(10)7(11)2-5(4)9/h1-2H,3H2
CAS DataBase Reference 157911-56-3(CAS DataBase Reference)

Safety information for 2,4,5-Trifluorobenzyl bromide

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
H318:Serious eye damage/eye irritation
Precautionary Statement Codes P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 2,4,5-Trifluorobenzyl bromide

InChIKey GAUXEYCSWSMMFZ-UHFFFAOYSA-N
SMILES C1(CBr)=CC(F)=C(F)C=C1F

Related products of tetrahydrofuran

You may like

  • 157911-56-3 1-Bromomethyl-2,4,5-trifluorobenzene 99%
    157911-56-3 1-Bromomethyl-2,4,5-trifluorobenzene 99%
    157911-56-3
    View Details
  • 2,4,5-Trifluorobenzyl Bromide CAS 157911-56-3
    2,4,5-Trifluorobenzyl Bromide CAS 157911-56-3
    157911-56-3
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.