2,4-Dimethoxyaniline

CAS NO.：2735-04-8
Empirical Formula: C8H11NO2
Molecular Weight: 153.18
MDL number: MFCD00008371
EINECS: 220-355-7
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-01 18:09:03

What is 2,4-Dimethoxyaniline?

Chemical properties

black crystals

The Uses of 2,4-Dimethoxyaniline

Various 2,4-dimethoxyphenylsemicarbazones were synthesized starting from 2,4-dimethoxyaniline via a phenylcarbamate intermediate. The hydrochloride of 2,4-dimethoxyaniline was prepared by intro- ducing hydrogen chloride gas into an etheral solution and washing the precipitate with absolute diethyl ether.

Synthesis Reference(s)

Tetrahedron Letters, 34, p. 2441, 1993 DOI: 10.1016/S0040-4039(00)60436-7

General Description

Black crystalline solid.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

2,4-Dimethoxyaniline neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Health Hazard

ACUTE/CHRONIC HAZARDS: 2,4-Dimethoxyaniline is a local irritant.

Properties of 2,4-Dimethoxyaniline

Melting point:	33-36 °C (lit.)
Boiling point:	75-80 C
Density	1.075 g/mL at 25 °C (lit.)
refractive index	1.4640 (estimate)
Flash point:	>230 °F
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
form	Crystalline Solid
pka	5.14±0.10(Predicted)
color	Dark brown
Water Solubility	7 g/L (20 ºC)
BRN	638704
Stability:	Stability Stable, but sensitive to prolonged exposure to light. Incompatible with acids.
CAS DataBase Reference	2735-04-8(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 2,4-dimethoxy-(2735-04-8)
EPA Substance Registry System	2,4-Dimethoxyaniline (2735-04-8)

Safety information for 2,4-Dimethoxyaniline

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.