Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listPhenetidine

Phenetidine

Synonym(s):p-Phenetidine;4-Ethoxyaniline

  • CAS NO.:156-43-4
  • Empirical Formula: C8H11NO
  • Molecular Weight: 137.18
  • MDL number: MFCD00007865
  • EINECS: 205-855-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-28 16:27:48
Phenetidine Structural

What is Phenetidine?

Chemical properties

colourless liquid

The Uses of Phenetidine

A toxic metabolite of Phenacetin (P294580) which exhibits high renal toxicity. p-Phenetidine also reduced COX-1 and COX-2 expression in neutrophils.

Definition

ChEBI: An aromatic ether that is aniline in which the hydrogen at position 4 is replaced by an ethoxy group. It is a hydrolysis metabolite of phenacetin.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 27, p. 347, 1984 DOI: 10.1021/jm00369a019

General Description

Colorless to dark red liquid.

Air & Water Reactions

Very sensitive to exposure to air and light. Turns red to brown on exposure to light and air. . Slightly soluble in water.

Reactivity Profile

Phenetidine reacts vigorously with powerful oxidizers.

Fire Hazard

Phenetidine is combustible.

Safety Profile

Poison by inhalation. Moderately toxic by ingestion and intraperitoneal routes. Caution: It can be absorbed through the skin. A skin and eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Properties of Phenetidine

Melting point: 2-5 °C(lit.)
Boiling point: 250 °C(lit.)
Density  1.065 g/mL at 25 °C(lit.)
vapor pressure  2.93Pa at 25℃
refractive index  n20/D 1.559(lit.)
Flash point: 240 °F
storage temp.  2-8°C
solubility  20g/l
form  A liquid
pka 5.2(at 28℃)
color  Clear Yellow
PH 8 (1g/l, H2O, 20℃)
Water Solubility  practically insoluble
Sensitive  Air Sensitive
Merck  14,7228
BRN  606666
Dielectric constant 7.3(21℃)
Stability: Stable, but light and air sensitive. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference 156-43-4(CAS DataBase Reference)
NIST Chemistry Reference 4-Ethoxyaniline(156-43-4)
EPA Substance Registry System p-Phenetidine (156-43-4)

Safety information for Phenetidine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
H341:Germ cell mutagenicity
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for Phenetidine

InChIKey IMPPGHMHELILKG-UHFFFAOYSA-N

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.