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HomeProduct name list2,4-Dihydroxypyrimidine-5-carboxylic acid

2,4-Dihydroxypyrimidine-5-carboxylic acid

Synonym(s):Isoorotic acid;Uracil-5-carboxylic acid

  • CAS NO.:23945-44-0
  • Empirical Formula: C5H4N2O4
  • Molecular Weight: 156.1
  • MDL number: MFCD00006023
  • EINECS: 245-947-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
2,4-Dihydroxypyrimidine-5-carboxylic acid Structural

What is 2,4-Dihydroxypyrimidine-5-carboxylic acid?

Chemical properties

white to slightly yellow crystalline powder or

The Uses of 2,4-Dihydroxypyrimidine-5-carboxylic acid

2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been used for the visual sensing of melamine (at parts-per-billion (ppb) level) by a highly sensitive analytical method based on Au nanoparticles.

What are the applications of Application

2,4-Dihydroxypyrimidine-5-carboxylic acid is has been used for the visual sensing of melamine

Definition

ChEBI: Uracil-5-carboxylic acid is a pyrimidinemonocarboxylic acid that is uracil carrying a carboxy group at position 5. It is functionally related to a uracil. It is a conjugate acid of a uracil-5-carboxylate. It is a tautomer of a 2,4-dihydroxypyrimidine-5-carboxylic acid.

General Description

2,4-Dihydroxypyrimidine-5-carboxylic acid (Uracil-5-carboxylic acid) has been obtained from 5-formyluracil by the action of enzyme, thymine 7-hydroxylase. It has been used to synthesize N1-alkylated uracil derivatives.

Properties of 2,4-Dihydroxypyrimidine-5-carboxylic acid

Melting point: 283 °C (dec.)(lit.)
Boiling point: 280.29°C (rough estimate)
Density  1.6814 (rough estimate)
refractive index  1.4800 (estimate)
storage temp.  Inert atmosphere,Room Temperature
solubility  Soluble in DMSO
pka 5.08±0.20(Predicted)
form  Crystalline Powder
color  White to slightly yellow
Water Solubility  1.8g/L(20 ºC)
CAS DataBase Reference 23945-44-0(CAS DataBase Reference)
EPA Substance Registry System 5-Pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-2,4-dioxo- (23945-44-0)

Safety information for 2,4-Dihydroxypyrimidine-5-carboxylic acid

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 2,4-Dihydroxypyrimidine-5-carboxylic acid

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