23-HYDROXYBETULINIC ACID
- CAS NO.:85999-40-2
- Empirical Formula: C30H48O4
- Molecular Weight: 472.7
- MDL number: MFCD28126999
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-01-05 22:10:32
What is 23-HYDROXYBETULINIC ACID?
Description
23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity. It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 μM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC50 = 94.8 μM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels.
The Uses of 23-HYDROXYBETULINIC ACID
23-Hydroxybetulinic Acid is a potential cytoxic agent in the treatment of cancer. Apoptotic effect. Antiproliferative.
Definition
ChEBI: 23-Hydroxybetulinic acid is a triterpenoid. It has a role as a metabolite. It derives from a hydride of a lupane.
Properties of 23-HYDROXYBETULINIC ACID
Melting point: | >293°C (dec.) |
Boiling point: | 585.8±25.0 °C(Predicted) |
Density | 1.106 |
storage temp. | -20°C Freezer, Under inert atmosphere |
solubility | Methanol (Slightly, Heated), Pyridine (Slightly) |
form | Solid |
pka | 4.60±0.70(Predicted) |
color | White |
Safety information for 23-HYDROXYBETULINIC ACID
Computed Descriptors for 23-HYDROXYBETULINIC ACID
New Products
2,2-diethoxyethanethioamide Tubulysin C Potassium HMDS (1.0 M in THF) 1-(1,1-Difluoroethyl)-2-fluorobenzene Methyl (R)-1-Boc-4,4-difluoropyrrolidine-2-carboxylate 3-Aminocyclobutanone hydrochloride 2,2-Difluoropropanol tetrahydro-4-methyl-2H-pyran 2-(azetidin-3-ylidene)acetonitrile (hydrochloride) 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile Fuel shell Imeglimin Hydrochloride IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Calcium Sodium Phosphosilicate IH Latanoprostene Bunod Magnesium Trisilicate Lubiprostone Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
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