2,3-Dimethylaniline

Synonym(s):2,3-Dimethylaniline;2,3-Xylidine;3-Amino-o-xylene;CN-Cbl;vic.-o-Xylidine

CAS NO.：87-59-2
Empirical Formula: C8H11N
Molecular Weight: 121.18
MDL number: MFCD00007732
EINECS: 201-755-0
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

What is 2,3-Dimethylaniline?

Chemical properties

brown liquid

The Uses of 2,3-Dimethylaniline

Reagent used in the preparation of non-steroidal anti-inflammatory drugs, dyes and pesticides.

General Description

Dark brown liquid.

Air & Water Reactions

Slightly soluble in water.

Reactivity Profile

2,3-Dimethylaniline reacts with strong oxidizing agents and hypochlorite bleaches . Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Fire Hazard

2,3-Dimethylaniline is combustible.

Safety Profile

A poison. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also other xylidine entries.

Purification Methods

Purify vic-xylidine by conversion into a derivative (see below), recrystallise the derivative, decompose the derivative with aqueous NaOH and fractionally distil the liquid base. The acetyl derivative has m 135o (from EtOH), and the formyl derivative has m 102o (from EtOH). [Beilstein 12 H 1101, 12 III 2438, 12 IV 2497.]

Properties of 2,3-Dimethylaniline

Melting point:	2.5 °C (lit.)
Boiling point:	221-222 °C (lit.)
Density	0.993 g/mL at 25 °C (lit.)
vapor density	4.2 (vs air)
vapor pressure	0.13 hPa (25 °C)
refractive index	n20/D 1.569(lit.)
Flash point:	205 °F
storage temp.	Store below +30°C.
solubility	1.5g/l
form	Liquid
pka	pK1:4.70(+1) (25°C)
color	Clear yellow to red-brown
explosive limit	1-2.7%(V)
Water Solubility	30 g/L (20 ºC)
Merck	14,10084
BRN	742174
Stability:	Stable. Combustible. Incompatible with strong oxidizing agents. Reacts with hypochlorite bleaches. May be light sensitive.
CAS DataBase Reference	87-59-2(CAS DataBase Reference)
NIST Chemistry Reference	Benzenamine, 2,3-dimethyl-(87-59-2)
EPA Substance Registry System	2,3-Dimethylaniline (87-59-2)

Safety information for 2,3-Dimethylaniline

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 Environment GHS09
GHS Hazard Statements	H373:Specific target organ toxicity, repeated exposure H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.