2',3'-Dideoxyuridine
Synonym(s):ddU
- CAS NO.：5983-09-5
- Empirical Formula: C9H12N2O4
- Molecular Weight: 212.2
- MDL number: MFCD00013359
- EINECS: 2017-001-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:11
What is 2',3'-Dideoxyuridine?
Chemical properties
powder
The Uses of 2',3'-Dideoxyuridine
2’,3’-Dideoxyuridine can be used as prodrug precursors or in antisense oligonucleotide synthesis. Also, it can be used to synthesize ProTide derivatives and evaluated against HIV-1 and HIV-2.
The Uses of 2',3'-Dideoxyuridine
Research tool for antiviral and anticancer studies.
What are the applications of Application
2′,3′-Dideoxyuridine is a research tool for anticancer and antiviral studies
Definition
ChEBI: 2,3-dideoxyuridine is a pyrimidine 2',3'-dideoxyribonucleoside.
Properties of 2',3'-Dideoxyuridine
| Melting point: | 127-129 °C(lit.) |
| alpha | 34 º (C=0.4 IN H2O) |
| Density | 1.397±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 5 mg/ml |
| form | A solid |
| pka | 9.39±0.10(Predicted) |
| color | White to off-white |
| optical activity | [α]20/D +34°, c = 0.4 in H2O |
| BRN | 750592 |
| CAS DataBase Reference | 5983-09-5(CAS DataBase Reference) |
Safety information for 2',3'-Dideoxyuridine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2',3'-Dideoxyuridine
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