2',3'-Dideoxythymidine
Synonym(s):2′,3′-Dideoxythymidine;DDT
- CAS NO.：3416-05-5
- Empirical Formula: C10H14N2O4
- Molecular Weight: 226.23
- MDL number: MFCD00010570
- EINECS: 2017-001-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-25 20:04:51
What is 2',3'-Dideoxythymidine?
The Uses of 2',3'-Dideoxythymidine
3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor.
The Uses of 2',3'-Dideoxythymidine
Research tool for antiviral and anticancer studies.
Purification Methods
3'-Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson & Todd J Chem Soc 816 1955.]
Properties of 2',3'-Dideoxythymidine
| Melting point: | 155-156 °C(lit.) |
| alpha | 20 º (C=0.6 IN H2O) |
| Density | 1.332±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml |
| form | Powder |
| pka | 9.55±0.10(Predicted) |
| color | White to Pale Yellow |
| optical activity | [α]19/D +20.0°, c = 0.6 in H2O |
| BRN | 21884 |
| CAS DataBase Reference | 3416-05-5(CAS DataBase Reference) |
Safety information for 2',3'-Dideoxythymidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2',3'-Dideoxythymidine
| InChIKey | XKKCQTLDIPIRQD-JGVFFNPUSA-N |
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