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HomeProduct name list2',3'-Dideoxythymidine

2',3'-Dideoxythymidine

Synonym(s):2′,3′-Dideoxythymidine;DDT

  • CAS NO.:3416-05-5
  • Empirical Formula: C10H14N2O4
  • Molecular Weight: 226.23
  • MDL number: MFCD00010570
  • EINECS: 2017-001-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-25 20:04:51
2',3'-Dideoxythymidine Structural

What is 2',3'-Dideoxythymidine?

The Uses of 2',3'-Dideoxythymidine

3’-Deoxythymidine inhibits the ability of bacteriophage T7 to infect Escherichia coli by inhibiting phage DNA synthesis. Also, it is a precursor of DNA polymerase β inhibitor.

The Uses of 2',3'-Dideoxythymidine

Research tool for antiviral and anticancer studies.

Purification Methods

3'-Deoxyuridine is recrystallised from Me2CO/MeOH and is dried in a vacuum. [Michelson & Todd J Chem Soc 816 1955.]

Properties of 2',3'-Dideoxythymidine

Melting point: 155-156 °C(lit.)
alpha  20 º (C=0.6 IN H2O)
Density  1.332±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,2-8°C
solubility  DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml
form  Powder
pka 9.55±0.10(Predicted)
color  White to Pale Yellow
optical activity [α]19/D +20.0°, c = 0.6 in H2O
BRN  21884
CAS DataBase Reference 3416-05-5(CAS DataBase Reference)

Safety information for 2',3'-Dideoxythymidine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2',3'-Dideoxythymidine

InChIKey XKKCQTLDIPIRQD-JGVFFNPUSA-N

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