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HomeProduct name list2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE

2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE

2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE Structural

What is 2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE?

The Uses of 2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE

2’,3’-Dideoxy-2,3-didehydroadenosine (Didanosine EP Impurity I) is an impurity of Didanosine (D440950), which is a purine analog (1) which used as an antiviral agent. Classed as an anti-retroviral drug used in the treatment of HIV in ART therapy, it also may increase acetaminophen related hepatotoxicity by enhancing mitochrondrial dysfunction (2).

Properties of 2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE

Melting point: 187-189°C
Boiling point: 553.9±60.0 °C(Predicted)
Density  1.74±0.1 g/cm3(Predicted)
storage temp.  2-8°C(protect from light)
solubility  Soluble in DMSO
pka 14.28±0.10(Predicted)

Safety information for 2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2',3'-DIDEOXY-2',3'-DIDEHYDROADENOSINE

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