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HomeProduct name list2,2',5,5'-Tetrachlorobenzidine

2,2',5,5'-Tetrachlorobenzidine

Synonym(s):OIP3;PK3;PKM2;pyruvate kinase, muscle;TCB

  • CAS NO.:15721-02-5
  • Empirical Formula: C12H8Cl4N2
  • Molecular Weight: 322.02
  • MDL number: MFCD00043918
  • EINECS: 239-815-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
2,2',5,5'-Tetrachlorobenzidine Structural

What is 2,2',5,5'-Tetrachlorobenzidine?

Definition

ChEBI: 2,2',5,5'-Tetrachlorobenzidine is a member of biphenyls and a dichlorobenzene.

Production Methods

2,2' ,5,5' -Tetrachlorobenzidine is made by the reduction of 2,5-dichloronitrobenzene with zinc dust and sodium hydroxide solution. The subsequent rearrangement is carried out using sulfuric acid or hydrochloric acid. The dihydrochloride melts at 230 ℃. Tetrachlorobenzidine is marketed as the free base and is used to produce yellow pigments.

Safety Profile

Suspected carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits very toxic fumes of NO, and Cl-.

Properties of 2,2',5,5'-Tetrachlorobenzidine

Melting point: 135-140 °C(lit.)
Boiling point: 477.67°C (rough estimate)
Density  1.5309 (rough estimate)
refractive index  1.6000 (estimate)
storage temp.  -70°C
solubility  soluble in Methanol
form  powder to crystal
pka 1.58±0.13(Predicted)
color  Light yellow to Yellow to Orange
CAS DataBase Reference 15721-02-5(CAS DataBase Reference)
IARC 3 (Vol. 27, Sup 7) 1987
EPA Substance Registry System [1,1'-Biphenyl]-4,4'-diamine, 2,2',5,5'-tetrachloro- (15721-02-5)

Safety information for 2,2',5,5'-Tetrachlorobenzidine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for 2,2',5,5'-Tetrachlorobenzidine

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