2,2',5,5'-Tetrachlorobenzidine
Synonym(s):OIP3;PK3;PKM2;pyruvate kinase, muscle;TCB
- CAS NO.：15721-02-5
- Empirical Formula: C12H8Cl4N2
- Molecular Weight: 322.02
- MDL number: MFCD00043918
- EINECS: 239-815-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:08:57
What is 2,2',5,5'-Tetrachlorobenzidine?
Definition
ChEBI: 2,2',5,5'-Tetrachlorobenzidine is a member of biphenyls and a dichlorobenzene.
Production Methods
2,2' ,5,5' -Tetrachlorobenzidine is made by the reduction of 2,5-dichloronitrobenzene with zinc dust and sodium hydroxide solution. The subsequent rearrangement is carried out using sulfuric acid or hydrochloric acid. The dihydrochloride melts at 230 ℃. Tetrachlorobenzidine is marketed as the free base and is used to produce yellow pigments.
Safety Profile
Suspected carcinogen with experimental carcinogenic and tumorigenic data. When heated to decomposition it emits very toxic fumes of NO, and Cl-.
Properties of 2,2',5,5'-Tetrachlorobenzidine
| Melting point: | 135-140 °C(lit.) |
| Boiling point: | 477.67°C (rough estimate) |
| Density | 1.5309 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | -70°C |
| solubility | soluble in Methanol |
| form | powder to crystal |
| pka | 1.58±0.13(Predicted) |
| color | Light yellow to Yellow to Orange |
| CAS DataBase Reference | 15721-02-5(CAS DataBase Reference) |
| IARC | 3 (Vol. 27, Sup 7) 1987 |
| EPA Substance Registry System | [1,1'-Biphenyl]-4,4'-diamine, 2,2',5,5'-tetrachloro- (15721-02-5) |
Safety information for 2,2',5,5'-Tetrachlorobenzidine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for 2,2',5,5'-Tetrachlorobenzidine
2,2',5,5'-Tetrachlorobenzidine manufacturer
Metropolitan Eximchem Pvt Ltd (Metropolitan Group)
1Y
Phone:+912224081528
product: 15721-02-5 2,2',5,5'-Tetrachlorobenzidine 98%
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