2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Synonym(s):cycl-Isopropylidene methylmalonate;Methyl Meldrum’s acid;Methylmalonic acid cyclic isopropylidene ester
- CAS NO.:3709-18-0
- Empirical Formula: C7H10O4
- Molecular Weight: 158.15
- MDL number: MFCD00006637
- EINECS: 223-050-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-19 19:28:24
What is 2,2,5-Trimethyl-1,3-dioxane-4,6-dione?
Chemical properties
White to slightly pink crystalline powder
The Uses of 2,2,5-Trimethyl-1,3-dioxane-4,6-dione
2,2,5-Trimethyl-1,3-dioxane-4,6-dione is used as a reagent in the synthesis of 3'',4''-bis-difluoromethoxycinnamoylanthranilate (FT061) which is an orally-active antifibrotic agent that reduces albuminuria in rat models of progressive diabetic nephropathy.
The Uses of 2,2,5-Trimethyl-1,3-dioxane-4,6-dione
2,2,5-Trimethyl-1,3-dioxane-4,6-dione was used for trapping the adduct formed during the reaction between alkyl isocyanides and dialkyl acetylenedicarboxylates.
General Description
X-ray irradiated single crystals of 2,2,5-trimethyl-1,3-dioxane-4,6-dione have been investigated by electron spin resonance (ESR), electron nuclear double resonance (ENDOR) and electron-electron double resonance (ELDOR) spectra.
Properties of 2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Melting point: | 111-114 °C(lit.) |
Boiling point: | 203.22°C (rough estimate) |
Density | 1.1229 (rough estimate) |
refractive index | 1.4610 (estimate) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform, Methanol |
form | Solid |
pka | 13.14±0.40(Predicted) |
color | White to Off-White |
BRN | 124044 |
CAS DataBase Reference | 3709-18-0(CAS DataBase Reference) |
Safety information for 2,2,5-Trimethyl-1,3-dioxane-4,6-dione
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2,5-Trimethyl-1,3-dioxane-4,6-dione
InChIKey | KJMCAXYHYPDRAV-UHFFFAOYSA-N |
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
Methyl 3-(tert-butoxycarbonyl)furan-2-carboxylate
Kresoxim-methyl
Trimethyl borate
Diethyl methylmalonate
Diisopropyl malonate
Isopropylmalonic acid
Methyl acetate
Basic Violet 1
You may like
-
2,2,5-Trimethyl-1,3-dioxane-4,6-dione CAS 3709-18-0View Details
3709-18-0 -
2033-24-1 98%View Details
2033-24-1 -
1975-50-4 98%View Details
1975-50-4 -
2-HYDROXY BENZYL ALCOHOL 98%View Details
90-01-7 -
2-Chloro-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 221615-75-4 98%View Details
221615-75-4 -
61397-56-6 CIS BROMO BENZOATE 98%View Details
61397-56-6 -
14714-50-2 (2-Hydroxyphenyl)acetonitrile 98+View Details
14714-50-2 -
118753-70-1 98+View Details
118753-70-1
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.