2,2-Diphenylglycine
Synonym(s):2,2-Diphenylglycine
- CAS NO.：3060-50-2
- Empirical Formula: C14H13NO2
- Molecular Weight: 227.26
- MDL number: MFCD00008048
- EINECS: 221-299-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-07-14 15:27:00
What is 2,2-Diphenylglycine?
Description
2, 2-Diphenylglycine is a highly similar analogue and the simplest aromatic peptide. It can be used as a synthesis reagent for amination reactions. It is a useful intermediate in pharmaceutical and in organic synthesis. Its derivatives have been also be shown to exhibit anticonvulsants activity and can be used for the treatment of pain.
Chemical properties
white powder
The Uses of 2,2-Diphenylglycine
2,2-Diphenylglycine is used as a synthesis reagent for amination reactions. It acts as an intermediate in pharmaceutical and in organic synthesis.
References
And, Meital Reches, and E. Gazit. "Formation of Closed-Cage Nanostructures by Self-Assembly of Aromatic Dipeptides." Nano Letters 4.4(2006):581-585.
https://www.alfa.com/en/catalog/B22650/
Harris, Robert H. "New uses for amino acid anticonvulsants for treatment of pain." EP, WO/2002/015922. 2002.
Properties of 2,2-Diphenylglycine
| Melting point: | 245-247 °C (dec.) (lit.) |
| Boiling point: | 368.97°C (rough estimate) |
| Density | 1.231±0.06 g/cm3 (20 ºC 760 Torr) |
| refractive index | 1.5780 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly, Heated), Methanol (Slightly, Heated) |
| form | Powder |
| pka | 1.38±0.10(Predicted) |
| color | White |
| Water Solubility | It is sparingly soluble in water. |
| Stability: | Hygroscopic |
| CAS DataBase Reference | 3060-50-2(CAS DataBase Reference) |
Safety information for 2,2-Diphenylglycine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2,2-Diphenylglycine
| InChIKey | YBONNYNNFBAKLI-UHFFFAOYSA-N |
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