2-Thiohydantoin
Synonym(s):2-Thioxo-4-imidazolidinone;NSC 11772
- CAS NO.:503-87-7
- Empirical Formula: C3H4N2OS
- Molecular Weight: 116.14
- MDL number: MFCD00005277
- EINECS: 207-977-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:15
What is 2-Thiohydantoin?
Chemical properties
BROWN CRYSTALLINE POWDER
The Uses of 2-Thiohydantoin
2-Thiohydantoin is a useful synthetic intermediate. It is a reactant for synthesis of drugs with antidiabetic activity, barbituric acid and thiohydantoin derivatives with antimicrobial activity, and possible anticancer agents.
The Uses of 2-Thiohydantoin
Reactant for synthesis of:• ;Drugs with antidiabetic activity1• ;Barbituric acid and thiohydantoin derivatives with antimicrobial activity2• ;Possible anticancer agents3• ;Fibroblast growth factor receptor 1 kinase inhibitors4• ;HIV-1 integrase inhibitors5Reactant for persilylation6
The Uses of 2-Thiohydantoin
Reactant for synthesis of:
- Drugs with antidiabetic activity
- Barbituric acid and thiohydantoin derivatives with antimicrobial activity
- Possible anticancer agents
- Fibroblast growth factor receptor 1 kinase inhibitors
- HIV-1 integrase inhibitors
Reactant for persilylation
What are the applications of Application
2-Thiohydantoin is an inhibitor of Flg
Properties of 2-Thiohydantoin
Melting point: | 229-231 °C (dec.)(lit.) |
Density | 1.346 (estimate) |
vapor density | 4 (vs air) |
refractive index | 1.6550 (estimate) |
storage temp. | Room Temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Crystalline Powder |
pka | 8.50±0.10(Predicted) |
color | White |
CAS DataBase Reference | 503-87-7(CAS DataBase Reference) |
NIST Chemistry Reference | 4-Imidazolidinone, 2-thioxo-(503-87-7) |
EPA Substance Registry System | 4-Imidazolidinone, 2-thioxo- (503-87-7) |
Safety information for 2-Thiohydantoin
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Computed Descriptors for 2-Thiohydantoin
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