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HomeProduct name list2-PIPERIDYLMETHYLAMINE

2-PIPERIDYLMETHYLAMINE

Synonym(s):(RS)-1-(Piperidin-2-yl)methanamine;2-Piperidinemethanamine

  • CAS NO.:22990-77-8
  • Empirical Formula: C6H14N2
  • Molecular Weight: 114.19
  • MDL number: MFCD00129011
  • EINECS: 245-371-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-06-11 18:14:38
2-PIPERIDYLMETHYLAMINE Structural

What is 2-PIPERIDYLMETHYLAMINE?

The Uses of 2-PIPERIDYLMETHYLAMINE

2-Piperidinemethanamine is used in the synthesis of compounds exhibiting anti-osteoclast and anti-osteoblast activity. It also is used in the synthesis of potent antibacterial.

The Uses of 2-PIPERIDYLMETHYLAMINE

Reactant for reversible aminal formation

Reactant for synthesis of:

  • Annulated N-heterocyclic carbene ligands
  • M3 Muscarinic receptor antagonists
  • Selective 5-ht5A receptor antagonists
  • Ternary platinum(II) complexes

What are the applications of Application

2-(Aminomethyl)piperidine is a simple piperidine & useful synthetic reagent

Purification Methods

Dry (over Na2SO4) and distil the piperidine under vacuum from KOH. It has been purified via the Reinekate salt (m 173-174o) and its dipicrate salt (m 201o, from H2O). [Norton et al. J Am Chem Soc 68 1330 1946, Mortimer Aust J Chem 11 84 1958, Augustine J Am Chem Soc 81 4667 1959, Beilstein 22 III/IV 3765.]

Properties of 2-PIPERIDYLMETHYLAMINE

Boiling point: 63-66°C/12mm
Density  0.9406 g/mL at 25 °C
refractive index  1.4850
Flash point: 63-66°C/12mm
storage temp.  -20°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form  neat
pka 10.32±0.29(Predicted)
color  Clear Colorless
BRN  102994
CAS DataBase Reference 22990-77-8(CAS DataBase Reference)

Safety information for 2-PIPERIDYLMETHYLAMINE

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P363:Wash contaminated clothing before reuse.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for 2-PIPERIDYLMETHYLAMINE

InChIKey RHPBLLCTOLJFPH-UHFFFAOYSA-N

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