2-PHENYLMELATONIN
- CAS NO.：151889-03-1
- Empirical Formula: C19H20N2O2
- Molecular Weight: 308.37
- MDL number: MFCD00673896
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:08
What is 2-PHENYLMELATONIN?
The Uses of 2-PHENYLMELATONIN
2-Phenylmelatonin is a melatonin receptor binder with mixed agonist/antagonist activity.
What are the applications of Application
2-Phenylmelatonin is a melatonin receptor binder with mixed agonist/antagonist activity
Definition
ChEBI: N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide is a phenylindole.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 38, p. 1132, 1995 DOI: 10.1021/jm00007a010
Biological Activity
Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC 50 values for G protein activation in MT 1 and MT 2 -transfected cells are 65 and 58 pM respectively.
storage
Desiccate at +4°C
Properties of 2-PHENYLMELATONIN
| storage temp. | Desiccate at +4°C |
| solubility | Soluble to 100 mM in ethanol and to 100 mM in DMSO |
| form | Powder |
| color | Off-white to yellow |
Safety information for 2-PHENYLMELATONIN
Computed Descriptors for 2-PHENYLMELATONIN
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