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HomeProduct name list2-PHENYLMELATONIN

2-PHENYLMELATONIN

2-PHENYLMELATONIN Structural

What is 2-PHENYLMELATONIN?

The Uses of 2-PHENYLMELATONIN

2-Phenylmelatonin is a melatonin receptor binder with mixed agonist/antagonist activity.

What are the applications of Application

2-Phenylmelatonin is a melatonin receptor binder with mixed agonist/antagonist activity

Definition

ChEBI: N-[2-(5-methoxy-2-phenyl-1H-indol-3-yl)ethyl]acetamide is a phenylindole.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 38, p. 1132, 1995 DOI: 10.1021/jm00007a010

Biological Activity

Highly potent melatonin agonist; displays higher affinity and greater potency than melatonin itself. The EC 50 values for G protein activation in MT 1 and MT 2 -transfected cells are 65 and 58 pM respectively.

storage

Desiccate at +4°C

Properties of 2-PHENYLMELATONIN

storage temp.  Desiccate at +4°C
solubility  Soluble to 100 mM in ethanol and to 100 mM in DMSO
form  Powder
color  Off-white to yellow

Safety information for 2-PHENYLMELATONIN

Computed Descriptors for 2-PHENYLMELATONIN

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