Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list2-Nitrobenzyl bromide

2-Nitrobenzyl bromide

Synonym(s):α-Bromo-2-nitrotoluene

  • CAS NO.:3958-60-9
  • Empirical Formula: C7H6BrNO2
  • Molecular Weight: 216.03
  • MDL number: MFCD00007184
  • EINECS: 223-558-9
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-01-27 09:38:02
2-Nitrobenzyl bromide Structural

What is 2-Nitrobenzyl bromide?

Chemical properties

white to light yellow crystal powde

The Uses of 2-Nitrobenzyl bromide

2-Nitrobenzyl bromide was used for caging unprotected cysteine-containing or thiophosphorylated peptides in aqueous solution. It can be used in the synthesis of (R)- and (S)-3-amino-3,4-dihydro-1H-quinolin-2-one.

The Uses of 2-Nitrobenzyl bromide

2-Nitrobenzyl bromide is used in the preparation of S-2-nitrobenzyl-cysteine by reaction with L-cysteine. It is also used for the introduction of the 2-nitrobenzyl protecting group in organic synthesis. It plays an important role in the production of expectorant agent. Further, it is employed for caging unprotected cysteine-containing or thiophosphorylated peptides in aqueous solution. In addition to this, it is used in the preparation of (R)- and (S)-3-amino-3,4-dihydro-1H-quinolin-2-one.

What are the applications of Application

2-Nitrobenzyl bromide is a reagent used for caging unprotected cysteine and thiophosphoryl peptides in aqueous solution

Biochem/physiol Actions

2-Nitrobenzyl bromide reacts with L-cysteine to form S-2-nitrobenzyl-cysteine which was used for modification of ultra-low-gelling-temperature (ULGT) agarose.

Properties of 2-Nitrobenzyl bromide

Melting point: 44-46 °C (lit.)
Boiling point: 265.51°C (rough estimate)
Density  1.6841 (rough estimate)
refractive index  1.6120 (estimate)
Flash point: >230 °F
storage temp.  Inert atmosphere,2-8°C
solubility  Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form  Crystals or Crystalline Powder
color  Yellow to light brown
Water Solubility  insoluble
BRN  638991
Stability: Hygroscopic
CAS DataBase Reference 3958-60-9(CAS DataBase Reference)
NIST Chemistry Reference 2-Nitrobenzyl bromide(3958-60-9)

Safety information for 2-Nitrobenzyl bromide

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H314:Skin corrosion/irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

Computed Descriptors for 2-Nitrobenzyl bromide

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.