4-Bromomethyl-3-nitrobenzoic acid
- CAS NO.:55715-03-2
- Empirical Formula: C8H6BrNO4
- Molecular Weight: 260.04
- MDL number: MFCD00216575
- EINECS: 205-516-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-07 13:31:19
What is 4-Bromomethyl-3-nitrobenzoic acid?
Chemical properties
pale yellow to pink crystalline powder
The Uses of 4-Bromomethyl-3-nitrobenzoic acid
4-Bromomethyl-3-nitrobenzoic acid is used as a reactant in the synthesis of 4-bromomethyl-3-nitrobenzoic acid succinimide ester, 4-((2-(hydroxymethyl)phenyl amino)methyl)-3-nitrobenzoic acid, 4-(2-hydroxyethylmercaptylmethyl)-3-nitrobenzoic acid. It is also used as a thiol photo-deprotection reagent, a starting material in the synthesis of 2H-indazole based library using parallel solution-phase methods.
The Uses of 4-Bromomethyl-3-nitrobenzoic acid
Photolabile Nbb handle employed in solid-phase peptide synthesis:
General Description
4-Bromomethyl-3-nitrobenzoic acid (BNBA) is a benzoic acid derivative. It has been synthesized by the nitration of 4-bromomethylbenzoic acid using fuming nitric acid. It participates in the synthesis of 3,4-dihydro-2(1H)-quinazolinones and 3,4-dihydro-1H-quinazolin-2-thiones.
Properties of 4-Bromomethyl-3-nitrobenzoic acid
Melting point: | 127-130 °C (lit.) |
Boiling point: | 392°C |
Density | 1.814 |
refractive index | 1.6500 (estimate) |
Flash point: | 191°C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMF: soluble(lit.) |
pka | 3.42±0.10(Predicted) |
Water Solubility | Soluble in DMF and dichloromethane. Insoluble in water. |
BRN | 1970939 |
CAS DataBase Reference | 55715-03-2(CAS DataBase Reference) |
Safety information for 4-Bromomethyl-3-nitrobenzoic acid
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 |
GHS Hazard Statements |
H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 4-Bromomethyl-3-nitrobenzoic acid
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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