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HomeProduct name list2-METHOXY-5-NITROBENZYL BROMIDE

2-METHOXY-5-NITROBENZYL BROMIDE

Synonym(s):2-Bromomethyl-4-nitroanisole;Koshland’s Reagent II

2-METHOXY-5-NITROBENZYL BROMIDE Structural

What is 2-METHOXY-5-NITROBENZYL BROMIDE?

The Uses of 2-METHOXY-5-NITROBENZYL BROMIDE

2-Methoxy-5-nitrobenzyl bromide was used to modify tryptophan residues of mouse interferon to enhance their activity. It was also used as reagent for sulfhydryl modification.

General Description

2-Methoxy-5-nitrobenzyl bromide is a potential mechanism-based inactivator of enzymes that perform O-dealkylations.

Biochem/physiol Actions

2-Methoxy-5-nitrobenzyl bromide inactivates cytochrome P-450 in male rat liver microsomes.

Properties of 2-METHOXY-5-NITROBENZYL BROMIDE

Melting point: 76-78 °C(lit.)
Boiling point: 348.7±27.0 °C(Predicted)
Density  1.589±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C

Safety information for 2-METHOXY-5-NITROBENZYL BROMIDE

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
GHS Hazard Statements H314:Skin corrosion/irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P310:Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2-METHOXY-5-NITROBENZYL BROMIDE

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